Comparing MRI scanning techniques for staging gastric cancer
Comparative Study on the Value of Three DWI Scan Sequences of 3.0T Magnetic Resonance in Staging of Gastric Cancer
This study is testing which of three MRI scanning methods works best for accurately staging gastric cancer in patients before surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 129 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Yunnan Cancer Hospital Academic / other |
| Locations | 1 site (Kunming) |
| Trial ID | NCT06735105 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of three different diffusion-weighted imaging (DWI) sequences—conventional DWI, TSE-DWI, and ZOOMit-DWI—in accurately staging gastric cancer. It involves a prospective enrollment of 72 patients who will undergo preoperative MRI scans using a 3.0 T scanner. The study aims to assess image quality and T staging accuracy by comparing MRI results with postoperative pathological findings. Quantitative metrics such as ADC, SNR, and CNR will be analyzed to determine the best imaging technique for this purpose.
Who should consider this trial
Good fit: Ideal candidates are patients diagnosed with gastric cancer who meet specific MRI eligibility criteria.
Not a fit: Patients with serious comorbidities or those unable to tolerate MRI examinations may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved accuracy in staging gastric cancer, facilitating better treatment planning.
How similar studies have performed: While there is ongoing research in imaging techniques for gastric cancer, this specific comparison of DWI sequences is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. The patient was diagnosed with gastric cancer by pathological biopsy 2. No biopsy was taken within 1 week before MR Examination to rule out the effect of bleeding on the image 3. No contraindications for MRI examination; And exclude serious heart, liver, kidney, cerebrovascular diseases. Exclusion Criteria: 1. The image quality cannot meet the diagnostic criteria; 2. Patients could not tolerate MRI examination, resulting in incomplete MR-related sequence image data.
Where this trial is running
Kunming
- Yunnan Cancer Hospital — Kunming, China (Recruiting)
Study contacts
- Study coordinator: Li Yanli, master
- Email: lyl2241@163.com
- Phone: 18987958050
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.