Comparing MRI and CT for monitoring after heart surgery
Validation of Magnetic Resonance Imaging Against Multidetector Computed Tomography After Ross Procedure Using Loose Jacket Technique
This study is testing whether MRI scans can be a good alternative to CT scans for monitoring patients after they have heart surgery using the Ross procedure.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 70 (estimated) |
| Sex | All |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Aswān) |
| Trial ID | NCT06575556 on ClinicalTrials.gov |
What this trial studies
This study involves patients who have undergone the Ross procedure using the loose jacket technique. Participants will receive both cardiac CT and MRI scans to evaluate and compare the effectiveness of these imaging modalities in follow-up care. The goal is to determine whether MRI can serve as a viable alternative to CT for monitoring patients post-surgery. The study will include all eligible patients at the Aswan Heart Centre, focusing on their imaging results and overall outcomes.
Who should consider this trial
Good fit: Ideal candidates are patients who have undergone the Ross procedure with the loose jacket technique and meet the inclusion criteria.
Not a fit: Patients with contraindications for either cardiac CT or MRI, or those who underwent a different surgical technique, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a safer and more effective imaging option for patients after heart surgery.
How similar studies have performed: While there is ongoing research comparing imaging modalities, this specific approach focusing on the Ross procedure with the loose jacket technique is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients who underwent Ross procedure with loose jacket technique at Aswan Heart Centre, regardless of the indication and duration after surgery. * Patients should have survived until discharge and underwent at least one echocardiography with full data related to one or more anatomic subcomponents of the aortic root before surgery. Exclusion Criteria: * Patients who have contraindication for conducting cardiac CT scan. For instance, dye sensitivity, pregnancy, CKD, in addition to patients who have factors that interfere with CT image quality as metallic objects within the chest (e.g. Pacemaker). * Patients who have contra-indication for conducting a safe MRI scan. For instance, metallic implants that are incompatible with MRI. * Patients who underwent Ross procedure with technique other than loose jacket.
Where this trial is running
Aswān
- Aswan Heart Centre (Magdi Yacoub Foundation) — Aswān, Egypt (Recruiting)
Study contacts
- Principal investigator: Abdelrahman Gamal Ahmed G. Ramadan — Assiut University
- Study coordinator: Abdelrahman Gamal Ahmed Ramadan, MBBCH
- Email: abdelrahman.ramadan@aun.edu.eg
- Phone: 01011808028
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.