Comparing mirror therapy with electrical or binaural beat stimulation for stroke recovery

Comparison of Effects of Mirror Therapy Combined With Neuromuscular Electrical Stimulation or Binaural Beats Stimulation on Cortical Excitability, Heart Rate Variability and Lower Limb Motor Function in Patients With Stroke

NA · Kaohsiung Medical University Chung-Ho Memorial Hospital · NCT06011018

This study is testing whether combining mirror therapy with electrical stimulation or binaural beats can help stroke survivors improve their leg movement and overall recovery.

Quick facts

PhaseNA
Study typeInterventional
Enrollment72 (estimated)
Ages20 Years to 80 Years
SexAll
SponsorKaohsiung Medical University Chung-Ho Memorial Hospital (other)
Locations1 site (Kaohsiung City)
Trial IDNCT06011018 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of mirror therapy combined with either neuromuscular electrical stimulation or binaural beat stimulation in improving lower limb motor function in patients who have experienced a stroke. It will assess how these interventions affect cortical excitability and heart rate variability, providing insights into their potential benefits for motor recovery. Participants will be monitored for changes in motor function and related physiological parameters over the course of the study.

Who should consider this trial

Good fit: Ideal candidates are adults aged 20 to 80 who have had their first stroke at least 6 months prior and can sit independently for 30 minutes.

Not a fit: Patients with speech, hearing, or visual impairments, as well as those with other orthopedic diseases or complete sensory impairment, may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance recovery of motor function in stroke patients, leading to improved mobility and quality of life.

How similar studies have performed: While the combination of these therapies is innovative, similar studies have shown promise in using mirror therapy for motor recovery in stroke patients.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. First occurrence of stroke≧ 6 months
2. Mini-mental state examination≧24
3. Modified Ashworth's scale of ankle muscle ≦3
4. Sit independently≧30 mins
5. Brunnstrom stage ≧3
6. Aged between 20 and 80 years

Exclusion Criteria:

1. Speech impairment
2. Hearing impairment
3. Visual impairment
4. Other orthopedic diseases or nerve damage
5. Complete sensory impairment
6. Pacemaker or metal implants

Where this trial is running

Kaohsiung City

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Stroke, Healthy Adults

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.