Comparing mirabegron and solifenacin for treating overactive bladder in women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of two medications, mirabegron and solifenacin, on various aspects of overactive bladder syndrome in women. It specifically looks at psychological distress, sexual function, bladder wall thickness, and bladder blood flow. Participants will receive either medication to determine which is more effective in alleviating symptoms and improving quality of life. The study is designed as a Phase 3 interventional trial to provide robust data on the comparative effectiveness of these treatments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Overactive bladder syndrome

Exclusion Criteria:

* Allergy to mirabegron or solifenacin.
* Patients with severe hypertension who are difficult to control, known urethral diverticulum, known bladder malignant tumors, urinary retention patients, gastric retention patients, uncontrolled angular glaucoma patients, dialysis patients, severe renal dysfunction , moderate liver dysfunction, use strong inhibitors of CYP3A4 such as ketoconazole.

Where it's running

• Department of Obstetrics and Gynecology, Far-Eastern Memorial Hospital
  Banqiao, New Taipei, Taiwan Recruiting

Study contacts

• Study coordinator: Sheng-Mou Hsiao, MD
• Email: smhsiao2@gmail.com
• Phone: +886289667000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.