Comparing mini-invasive techniques for aortic surgery

Comparison Between Ministernotomy and Minithoracotomy for Aortic Surgery

Observational University of Florence · NCT04350697

This study is testing which of two mini-invasive surgical methods for aortic valve replacement works better for patients needing this surgery.

Quick facts

Study typeObservational
Enrollment2425 (estimated)
Ages18 Years to 90 Years
SexAll
SponsorUniversity of Florence Academic / other
Locations1 site (Florence)
Trial IDNCT04350697 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate and compare the immediate and long-term outcomes of two mini-invasive surgical techniques used for aortic valve replacement: ministernotomy and anterior right minithoracotomy. By observing patients who are indicated for aortic and/or aortic valve surgery, the study seeks to determine if one technique offers superior results over the other. The research is observational in nature, focusing on real-world outcomes rather than controlled interventions.

Who should consider this trial

Good fit: Ideal candidates for this study are patients who require aortic and/or aortic valve surgery.

Not a fit: Patients who do not require aortic surgery or have contraindications for surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify the most effective surgical approach for aortic valve replacement, leading to improved patient outcomes.

How similar studies have performed: While there have been studies on mini-invasive surgical techniques, this specific comparison of ministernotomy and minithoracotomy is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

- Indication for Aortic and/or Aortic Valve surgery

Exclusion Criteria:

- none

Where this trial is running

Florence

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions SurgerySurgical InjurySurgical Procedure, UnspecifiedSurgical IncisionAortic Surgeryminiinvasive surgeryaortic surgeryminithoracotomy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.