Comparing Midline Catheters and Central Venous Catheters for Patients with Difficult Intravenous Access

Central Venous Catheter vs Midline in Difficulty Access Patient - A Randomized Controlled Clinical Pilot Trial - Pilot-ACCESS-D

Not applicable Interventional Region Jönköping County · NCT06719869

This study is testing whether Midline catheters work better than Central Venous Catheters for hospitalized patients who have trouble getting IV access.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorRegion Jönköping County Government
Drugs / interventionschemotherapy
Locations1 site (Jönköping, Region Jönköping)
Trial IDNCT06719869 on ClinicalTrials.gov

What this trial studies

This pilot trial aims to evaluate the effectiveness of Midline catheters versus Central Venous Catheters (CVC) in patients who have difficulty establishing intravenous access. The study will involve 30 hospitalized patients who meet specific criteria for difficult intravenous access, as assessed by trained clinicians. Participants will be randomly assigned to receive either a Midline catheter or a CVC, both guided by ultrasound, in a controlled setting at Ryhov County Hospital in Sweden. The trial follows CONSORT guidelines for pilot studies to ensure rigorous methodology and patient safety.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and over who have a history of difficult intravenous access or have failed multiple attempts at establishing peripheral access.

Not a fit: Patients who are unable to communicate in Scandinavian languages, have cognitive impairments, or are receiving hyperosmolar solutions or chemotherapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the comfort and experience of patients requiring intravenous access by reducing the number of needle sticks and complications.

How similar studies have performed: While this approach is being tested in this pilot trial, similar studies have shown promise in improving intravenous access techniques, suggesting potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • Age 18 and over

  * DIVA criterium fulfilled;

    * 2 attempts of venous access by 2 clinicians OR
    * No visible nor palpable veins OR
    * History of difficult venous access
  * 4 - 29 days of catheter dwell time anticipated as assessed by referring clinician.

Exclusion Criteria:

* Unable to speak Scandinavian
* Cognitive Impairment
* Is to receive hyperosmolar solutions (600 milliosmoles/L or above).
* Is to receive chemotherapy

Where this trial is running

Jönköping, Region Jönköping

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Difficult Intravenous Accesscentral venous catheterizationmidlinedifficult intravenous accessrandomised controlled trialpilot trial
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.