Comparing microneedling alone versus with hyaluronic acid for thin gums
Comparative Evaluation Of Microneedling Alone vs Microneedling Along With Hyaluronic Acid In Thin Gingival Phenotype: A Split Mouth Randomized Clinical Trial
This study is testing whether adding hyaluronic acid to microneedling can help people with thin gums get thicker and healthier gums.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Sponsor | Postgraduate Institute of Dental Sciences Rohtak Academic / other |
| Locations | 1 site (Rohtak, Haryana) |
| Trial ID | NCT05869136 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of microneedling alone compared to microneedling combined with hyaluronic acid in increasing gingival thickness in patients with a thin gingival phenotype. The study will recruit 20 systematically healthy patients who exhibit thin gingival tissue thickness of less than 1mm in the mandibular anterior region. Participants will undergo a randomized controlled trial over 24 months, assessing the outcomes based on established periodontal health indices. The goal is to determine if the addition of hyaluronic acid enhances the benefits of microneedling in improving gingival health.
Who should consider this trial
Good fit: Ideal candidates are healthy individuals with a thin gingival phenotype and gingival tissue thickness of less than 1mm.
Not a fit: Patients with systemic diseases, previous periodontal surgery, or those using medications that affect periodontal outcomes may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a less invasive and more effective treatment option for patients with thin gingival phenotypes, potentially reducing the risk of gingival recession.
How similar studies have performed: Previous studies have shown promising results with microneedling and hyaluronic acid in enhancing gingival thickness, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: • Thin gingival phenotype with gingival tissue thickness \<1mm in mandibular anteriors All the patients will be subjected to phase-I therapy and will be included after achieving healthy gingiva with Plaque index (Silness \& Loe) \<1, gingival index (Loe \& Silness) \<1 and showing adequate compliance and willing to participate in the study. Exclusion Criteria: * Patients having systemic diseases such as hypertension, diabetes, hyperthyroidism or on medications that influence the outcome of periodontal procedure * Smokers, tobacco users * Previous periodontal surgery * No haematological disorders. * Use of blood thinners * Use of any drugs that might lead to gingival enlargement * Stress, bruxism
Where this trial is running
Rohtak, Haryana
- Post Graduate Institute of Dental Sciences — Rohtak, Haryana, India (Recruiting)
Study contacts
- Principal investigator: Dr Nishi Tanwar, MDS — Post graduate institute of dental sciences,Rohtak,Haryana,India
- Study coordinator: Dr Sanjay Tewari, MDS
- Email: principalpgids@yahoo.in
- Phone: 9416259534
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.