Comparing micro-ultrasound and MRI for prostate cancer screening

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of high-resolution micro-ultrasound compared to multiparametric magnetic resonance imaging (MRI) for screening prostate cancer. Participants will be randomly assigned to receive either imaging modality to determine which is more effective in guiding decisions about prostate biopsies. The study focuses on men aged 50 to 70 with specific prostate health indicators, ensuring a targeted approach to screening. By comparing these two imaging techniques, the study seeks to improve prostate cancer detection methods.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Male sex;
2. Age 50-70;
3. PSA 3-20 and/or abnormal DRE;
4. Biopsy naïve.

Exclusion Criteria:

1. Prior personal history of prostate cancer;
2. Prior prostate imaging using microUS or MRI;
3. Contraindication to microUS or MRI;
4. Testosterone replacement therapy within last 12 months; or
5. Androgen deprivation therapy within last 12 months.

Where it's running

• University of California, Los Angeles (UCLA)
  Los Angeles, California, United States Recruiting
• University of British Columbia
  Vancouver, British Columbia, Canada Recruiting
• Sunnybrook Health Sciences Centre
  Toronto, Ontario, Canada Recruiting
• CH de Martigues
  Martigues, France Recruiting
• Vestfold Hospital Trust
  Tønsberg, Norway Recruiting
• Urologia Clinica Bilbao
  Bilbao, Spain Recruiting

Study contacts

• Principal investigator: Adam Kinnaird, MD, PhD — University of Alberta
• Study coordinator: Stacey Broomfield, PhD
• Email: sbroomfi@ualberta.ca
• Phone: +1-780-407-5800

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.