Comparing Low Carbohydrate and Mediterranean Diets for Adolescents with Type 1 Diabetes

Low Carbohydrate Versus Mediterranean Diet in Adolescents With Type 1 Diabetes: A Randomized Control Trial

NA · Sheba Medical Center · NCT05872711

This study tests whether a low carbohydrate diet or a Mediterranean diet helps teenagers with type 1 diabetes manage their blood sugar better over six months.

Quick facts

PhaseNA
Study typeInterventional
Enrollment40 (estimated)
Ages12 Years to 22 Years
SexAll
SponsorSheba Medical Center (other gov)
Locations1 site (Ramat Gan)
Trial IDNCT05872711 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to compare the effects of a low carbohydrate diet versus a Mediterranean diet on glycemic control in adolescents with type 1 diabetes. Participants will be randomly assigned to one of the two diet groups and will receive dietary education and support throughout the six-month study period. The trial will assess various health metrics, including blood sugar levels, lipid profiles, and microbiome changes, while also evaluating the safety and adherence to the diets. Blood work and stool samples will be collected at multiple points to monitor health outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are adolescents diagnosed with type 1 diabetes who are using continuous glucose monitoring.

Not a fit: Patients with a history of eating disorders or family history of mental disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into effective dietary management strategies for adolescents with type 1 diabetes, potentially improving their glycemic control.

How similar studies have performed: Other studies have shown promising results with dietary interventions in diabetes management, but this specific comparison of low carbohydrate versus Mediterranean diets in adolescents is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Type 1 diabetes
* Connected to a continuous glucose monitoring (CGM)

Exclusion Criteria:

* History of eating disorder
* Family history of mental disorders

Where this trial is running

Ramat Gan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Type 1 Diabetes, Adolescents, Glycemic targets, Low carbohydrate diet, Mediterranean diet

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.