Comparing low and high sodium levels in dialysis to see how it affects recovery time
Official title: Effect of Low Versus High Dialysate Sodium Concentration During Hemodialysis on Dialysis Recovery Time: A Prospective Randomized Clinical Trial
Run by Alexandria University · NCT05418647 · Data updated 2026-11-12
This study is testing whether using low or high sodium levels in dialysis can help people with chronic kidney disease recover faster after their treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Alexandria University Academic / other |
| Locations | 2 sites (Alexandria and 1 other locations) |
| Status | Recruiting |
| Started | April 15, 2025 |
| Main results expected | July 15, 2025 |
| Study ends | August 15, 2025 |
| Registry record updated | February 11, 2025 |
| Trial ID | NCT05418647 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older with end-stage renal disease on long-term hemodialysis for more than 90 days.
✕Probably not a fit
Patients with reading or hearing difficulties, unstable clinical conditions, dementia, active malignancy, or liver failure may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This research evaluates the impact of low versus high sodium concentration in dialysate during hemodialysis on the recovery time of patients. It focuses on individuals with chronic kidney disease who undergo long-term hemodialysis, aiming to address the prevalent issue of fatigue post-treatment. By measuring the time it takes for patients to recover after dialysis sessions, the study seeks to identify optimal sodium levels that may enhance patient quality of life. The study involves patients aged 18 and older who have been on hemodialysis for at least 90 days.
Why it matters
Potential benefit: If successful, this study could lead to improved recovery times and overall quality of life for patients undergoing hemodialysis.
How similar studies have gone: Previous studies have indicated a potential link between dialysate sodium levels and recovery time, suggesting this approach may yield beneficial insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with end-stage renal disease who have been prescribed long term hemodialysis and undergo four-hour HD treatments three times a week for more than 90 days. * Patient must be at least 18 years old. They must be able to read and write, as well as be in complete mental health. Exclusion Criteria: * Inability to complete the surveys due to reading or hearing difficulties, actual instability of clinical condition that necessitate hospitalization, dementia, active malignancy or liver failure.
Where it's running
-
Faculty of Medicine, Alexandria University
Alexandria, Egypt Recruiting -
Faculty of Medicine, Aexandria University
Alexandria, Egypt Not yet recruiting
Study contacts
- Principal investigator: Mohamed Mamdouh Elsayed, MD — lecturer
- Study coordinator: Mohamed Mamdouh Elsayed, MD
- Email: dr_mohamedmamdouh87@yahoo.com
- Phone: 00201068055103
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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This project will collect and compare data on adults in ICUs across Latin America who need dialysis for severe acute kidney injury to see how they are treated and what outcomes they have.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.