Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Comparing low and high sodium levels in dialysis to see how it affects recovery time

Official title: Effect of Low Versus High Dialysate Sodium Concentration During Hemodialysis on Dialysis Recovery Time: A Prospective Randomized Clinical Trial

Run by Alexandria University · NCT05418647 · Data updated 2026-11-12

This study is testing whether using low or high sodium levels in dialysis can help people with chronic kidney disease recover faster after their treatment.

More Dialysis trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment40 (estimated)
SponsorAlexandria University
Academic / other
Locations2 sites (Alexandria and 1 other locations)
StatusRecruiting
StartedApril 15, 2025
Main results expectedJuly 15, 2025
Study endsAugust 15, 2025
Registry record updatedFebruary 11, 2025
Trial IDNCT05418647 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older with end-stage renal disease on long-term hemodialysis for more than 90 days.

Probably not a fit

Patients with reading or hearing difficulties, unstable clinical conditions, dementia, active malignancy, or liver failure may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research evaluates the impact of low versus high sodium concentration in dialysate during hemodialysis on the recovery time of patients. It focuses on individuals with chronic kidney disease who undergo long-term hemodialysis, aiming to address the prevalent issue of fatigue post-treatment. By measuring the time it takes for patients to recover after dialysis sessions, the study seeks to identify optimal sodium levels that may enhance patient quality of life. The study involves patients aged 18 and older who have been on hemodialysis for at least 90 days.

Why it matters

Potential benefit: If successful, this study could lead to improved recovery times and overall quality of life for patients undergoing hemodialysis.

How similar studies have gone: Previous studies have indicated a potential link between dialysate sodium levels and recovery time, suggesting this approach may yield beneficial insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with end-stage renal disease who have been prescribed long term hemodialysis and undergo four-hour HD treatments three times a week for more than 90 days.
* Patient must be at least 18 years old. They must be able to read and write, as well as be in complete mental health.

Exclusion Criteria:

* Inability to complete the surveys due to reading or hearing difficulties, actual instability of clinical condition that necessitate hospitalization, dementia, active malignancy or liver failure.

Where it's running

  • Faculty of Medicine, Alexandria University
    Alexandria, Egypt
    Recruiting
  • Faculty of Medicine, Aexandria University
    Alexandria, Egypt
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.