Comparing low and high sodium levels in dialysis to see how it affects recovery time
Effect of Low Versus High Dialysate Sodium Concentration During Hemodialysis on Dialysis Recovery Time: A Prospective Randomized Clinical Trial
This study is testing whether using low or high sodium levels in dialysis can help people with chronic kidney disease recover faster after their treatment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Alexandria University Academic / other |
| Locations | 2 sites (Alexandria and 1 other locations) |
| Trial ID | NCT05418647 on ClinicalTrials.gov |
What this trial studies
This research evaluates the impact of low versus high sodium concentration in dialysate during hemodialysis on the recovery time of patients. It focuses on individuals with chronic kidney disease who undergo long-term hemodialysis, aiming to address the prevalent issue of fatigue post-treatment. By measuring the time it takes for patients to recover after dialysis sessions, the study seeks to identify optimal sodium levels that may enhance patient quality of life. The study involves patients aged 18 and older who have been on hemodialysis for at least 90 days.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with end-stage renal disease on long-term hemodialysis for more than 90 days.
Not a fit: Patients with reading or hearing difficulties, unstable clinical conditions, dementia, active malignancy, or liver failure may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved recovery times and overall quality of life for patients undergoing hemodialysis.
How similar studies have performed: Previous studies have indicated a potential link between dialysate sodium levels and recovery time, suggesting this approach may yield beneficial insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with end-stage renal disease who have been prescribed long term hemodialysis and undergo four-hour HD treatments three times a week for more than 90 days. * Patient must be at least 18 years old. They must be able to read and write, as well as be in complete mental health. Exclusion Criteria: * Inability to complete the surveys due to reading or hearing difficulties, actual instability of clinical condition that necessitate hospitalization, dementia, active malignancy or liver failure.
Where this trial is running
Alexandria and 1 other locations
- Faculty of Medicine, Aexandria University — Alexandria, Egypt (Not_yet_recruiting)
- Faculty of Medicine, Alexandria University — Alexandria, Egypt (Recruiting)
Study contacts
- Principal investigator: Mohamed Mamdouh Elsayed, MD — lecturer
- Study coordinator: Mohamed Mamdouh Elsayed, MD
- Email: dr_mohamedmamdouh87@yahoo.com
- Phone: 00201068055103
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.