Comparing low and high pressure during laparoscopic gallbladder surgery

Comparison Between Low Pressure Pneumoperitoneum with High Pressure Pneumoperitoneum in Post-operative Pain, Shoulder Tip Pain and Common Bile Duct Injuries in Patients Undergoing Laparoscopic Cholecystectomy

NA · Gulab Devi Hospital · NCT06447545

This study is testing whether using lower or higher pressure during gallbladder surgery can help reduce pain and complications for patients after the procedure.

Quick facts

PhaseNA
Study typeInterventional
Enrollment82 (estimated)
SexAll
SponsorGulab Devi Hospital (other)
Locations1 site (Lahore, PUN)
Trial IDNCT06447545 on ClinicalTrials.gov

What this trial studies

This study compares the effects of low pressure pneumoperitoneum (6-10 mmHg) versus high pressure pneumoperitoneum (12-15 mmHg) on postoperative pain, shoulder tip pain, and common bile duct injuries in patients undergoing laparoscopic cholecystectomy. The research aims to fill a knowledge gap regarding the incidence of these complications associated with different pressure settings during surgery. By analyzing patient outcomes, the study seeks to determine which pressure setting may lead to better recovery experiences for patients undergoing gallbladder removal. The findings could provide valuable insights into optimizing surgical techniques for improved patient care.

Who should consider this trial

Good fit: Ideal candidates for this study are patients of both genders who are scheduled for laparoscopic cholecystectomy due to cholelithiasis.

Not a fit: Patients with cardiac abnormalities or those who have had previous abdominal surgeries may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to reduced postoperative pain and complications for patients undergoing laparoscopic cholecystectomy.

How similar studies have performed: While there is limited data on this specific comparison, similar studies have explored the effects of pneumoperitoneum pressure on surgical outcomes, indicating potential for meaningful insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients from both genders
* Patients undergoing laparoscopic cholecystectomy for cholelithiasis.

Exclusion Criteria:

* Patients with cardiac abnormalities.
* Patients with previous abdominal surgeries.

Where this trial is running

Lahore, PUN

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Cholecystectomy, Pneumoperitoneum, Pain, Postoperative

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.