Comparing light therapies for treating meibomian gland dysfunction
Efficacy of Adjunctive Low-Level Light Therapy to Intense Pulsed Light for Meibomian Gland Dysfunction
This study is testing if combining low-level light therapy with intense pulsed light can help people with meibomian gland dysfunction feel better compared to just using intense pulsed light alone.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 58 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Chulalongkorn University Academic / other |
| Locations | 1 site (Bangkok) |
| Trial ID | NCT06468930 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of combining low-level light therapy (LLLT) with intense pulsed light (IPL) compared to IPL alone in treating meibomian gland dysfunction (MGD). Participants will be randomly assigned to receive either the combined treatment or IPL only, with both groups also receiving standard care including warm compresses and lid hygiene. The study will assess whether the addition of LLLT enhances treatment outcomes for patients suffering from MGD.
Who should consider this trial
Good fit: Ideal candidates are individuals with moderate to severe meibomian gland dysfunction and Fitzpatrick skin types 1-4.
Not a fit: Patients with recent ocular trauma, contact lens wearers, or those with uncontrolled ocular or systemic diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a more effective treatment option for patients with meibomian gland dysfunction.
How similar studies have performed: While the combination of LLLT and IPL is a novel approach, previous studies have shown success with IPL alone in treating MGD.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * MGD severity level 2 and above according to the international workshop on MGD * Fitzpatrick skin type of 1-4 according to sun sensitivity characteristics and appearance of the skin color Exclusion Criteria: * History of previous ocular trauma or surgery within the past six months * Contact lens-wearing patients * Patients with skin-pigmented lesions in the treatment area * Pregnancy or breastfeeding patients * Patients with any uncontrolled ocular or systemic diseases
Where this trial is running
Bangkok
- King Chulalongkorn memorial hospital — Bangkok, Thailand (Recruiting)
Study contacts
- Principal investigator: Chatchada Kharuhayothin — Ophthalmology department, Faculty of medicine, Chulalongkorn university
- Study coordinator: Chatchada Kharuhayothin
- Email: chatchada.kharuhayothin@gmail.com
- Phone: +66922496151
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.