Comparing Lasotronix and CPP-ACP for treating dentin hypersensitivity
A Clinical Study to Evaluate the Effectiveness of Casein Phosphopeptide, Amorphous Calcium Phosphate Paste (CPP-ACP) Used Alone or in Combination With Lasotronix (Diode Laser) to Treat Dentin Hypersensitivity
NA · Dow University of Health Sciences · NCT06463938
This study is testing whether a new toothpaste and a laser treatment can help people aged 25-65 with sensitive teeth feel better.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 25 Years to 65 Years |
| Sex | All |
| Sponsor | Dow University of Health Sciences (other) |
| Locations | 1 site (Karachi, Sindh) |
| Trial ID | NCT06463938 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of Casein phospho peptide paste (CPP-ACP) used alone or in combination with a diode laser (Lasotronix) in treating dentin hypersensitivity (DH). The study will involve patients aged 25-65 who have hypersensitive teeth without carious lesions. The methodology includes applying the laser to block pain in dentinal tubules and using CPP-ACP to occlude tubules, potentially improving patient outcomes. The trial is conducted at Dow University of Health Sciences in Karachi, Pakistan.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 25-65 with at least one hypersensitive and vital tooth without carious lesions.
Not a fit: Patients who have undergone desensitizing therapy in the last six months or have a history of smoking may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly reduce pain associated with dentin hypersensitivity for affected patients.
How similar studies have performed: While laser treatments for dentin hypersensitivity have been explored, the specific combination of Lasotronix and CPP-ACP is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * Patients of either gender, with ages between 25-65 years * should have at least more than one hypersensitive and vital tooth without any carious lesion or defective restoration Exclusion criteria: * History of desensitizing therapy on the affected tooth/teeth in last six months (use of desensitizing toothpaste) * use of antibiotics /analgesic/anti-inflammatory drugs * history of smoking * pregnancy * those who are not willing to participate or give follow-ups
Where this trial is running
Karachi, Sindh
- Dr Sanam Faheem — Karachi, Sindh, Pakistan (RECRUITING)
Study contacts
- Study coordinator: Sanam Dr Faheem, MSc
- Email: sanam.faheem@duhs.edu.pk
- Phone: 021-38771000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Dentin Sensitivity, Hypersensitivity, Cervical Lesion, Lasotronix, Diode laser