Comparing laser and electrocoagulation treatments for genital warts
Carbon Dioxide Laser Ablation Versus Electrocoagulation - a Prospective, Randomized Multicenter Trial Comparing Two Surgical Treatments in Women Undergoing Therapy for Condyloma Acuminata
This study is testing whether laser treatment or electrocoagulation is better for treating genital warts in women by looking at how well each method works and how patients feel about the results.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 114 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Zydolab - Institute of Cytology and Immune Cytochemistry Academic / other |
| Locations | 1 site (Herne, North Rhine-Westphalia) |
| Trial ID | NCT02520986 on ClinicalTrials.gov |
What this trial studies
This clinical trial compares two surgical methods for treating condyloma acuminata in women: carbon dioxide laser ablation and electrocoagulation. A total of 114 participants will be randomly assigned to receive one of the two treatments. The primary outcome will assess cosmetic results six weeks post-treatment using a visual analogue scale, while secondary outcomes will evaluate intervention time, complications, satisfaction, postoperative pain, and recurrence rates of genital warts.
Who should consider this trial
Good fit: Ideal candidates for this study are women diagnosed with condyloma acuminata who can provide informed consent.
Not a fit: Patients who are pregnant, have significant language barriers, or have certain medical conditions such as HIV or malignancies may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into the most effective treatment method for genital warts, improving patient outcomes and satisfaction.
How similar studies have performed: Previous studies have explored various treatment methods for condyloma acuminata, but this specific comparison of laser versus electrocoagulation is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * informed consent * women with anogenital affection of condyloma acuminata Exclusion Criteria: * significant language barrier * pregnancy * unwillingness to participate * the use of blood thinner or known coagulation disorder * the use of immunosuppressive medicament * HIV-Infection * malignant diseases * local therapy within 8 weeks before Treatment * wound healing disorder
Where this trial is running
Herne, North Rhine-Westphalia
- Department of Obstetrics and Gynecology of the Ruhr University Bochum — Herne, North Rhine-Westphalia, Germany (Recruiting)
Study contacts
- Principal investigator: Ziad Hilal, Dr. med. — Zydolab - Institute of Cytology and Immune Cytochemistry
- Study coordinator: Ziad Hilal, Dr. med.
- Email: z.hilal@zydolab.de
- Phone: +49231529747
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.