Comparing Laringocel® and C‑MAC® video laryngoscopes for placing breathing tubes during elective surgery

Estimation of the Non-Inferiority of the Laringocel® Videolaryngoscope Compared With the C-MAC D-BLADE (Karl Storz®) for First-Attempt Intubation in Adult Patients Undergoing Elective Surgery

Not applicable Interventional Universidad de Antioquia · NCT07239141

This comparison will test whether the Colombian Laringocel® video laryngoscope works as well as the C‑MAC D‑Blade® to help anesthesiologists place breathing tubes in adults having elective surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment252 (estimated)
Ages18 Years and up
SexAll
SponsorUniversidad de Antioquia Academic / other
Locations1 site (Medellín, Antioquia)
Trial IDNCT07239141 on ClinicalTrials.gov

What this trial studies

This randomized, single-center trial will enroll 252 adults undergoing elective surgery at Hospital Alma Máter de Antioquia and assign them 1:1 to intubation with either Laringocel® or the C‑MAC D‑Blade®. Only trained anesthesiologists will perform orotracheal intubation using the assigned video laryngoscope. The primary outcome is first-attempt intubation success (first-pass rate), with procedural details and safety data recorded for each case. The goal is to determine whether the locally made Laringocel® performs similarly to the widely used C‑MAC device and could offer a lower-cost option.

Who should consider this trial

Good fit: Adults aged 18 and older scheduled for elective surgery under general anesthesia who require single-lumen orotracheal intubation and meet standard preoperative fasting and anesthesia criteria.

Not a fit: Patients with an anticipated difficult airway (more than two anatomical risk factors) or those undergoing non-elective/emergency procedures are excluded and unlikely to benefit from this comparison.

Why it matters

Potential benefit: If Laringocel® performs similarly, it could offer hospitals a more affordable video laryngoscope option without sacrificing first-attempt intubation success.

How similar studies have performed: Video laryngoscopy is well established and many devices have improved first-pass intubation rates in prior trials, but direct randomized comparisons involving the Laringocel® are limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients 18 years of age or older
* Patients scheduled for elective surgery under general anesthesia
* Patients requiring single-lumen orotracheal intubation
* Patients compliant with the anesthetic indication and standard preoperative fasting requirements

Exclusion Criteria:

* Patients with an anticipated difficult airway (more than two anatomical risk factors for difficult airway)
* Patient refusal to participate in the study via informed consent

Where this trial is running

Medellín, Antioquia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Airway ManagementIntubation, EndotrachealVideolaryngoscopy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.