Comparing laparoscopic and vaginal methods for closing vaginal vault prolapse

Laparoscopic Versus Vaginal Approach Closure Complications of Vaginal Vault in Laparoscopic Hysterectomy

Not applicable Interventional Egymedicalpedia · NCT05960292

This study is testing whether closing vaginal vault prolapse with laparoscopic or vaginal methods leads to fewer complications and better sexual function for women aged 40 to 80 having a hysterectomy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment56 (estimated)
Ages40 Years to 80 Years
SexFemale
SponsorEgymedicalpedia Industry-sponsored
Locations1 site (Cairo)
Trial IDNCT05960292 on ClinicalTrials.gov

What this trial studies

This study investigates the differences in closure complications between laparoscopic and vaginal approaches during total laparoscopic hysterectomy for women with vaginal vault prolapse. It aims to assess the impact of these surgical techniques on female sexual function and the occurrence of vaginal cuff dehiscence, a serious complication. The study includes patients aged 40 to 80 who are undergoing laparoscopic hysterectomy due to various gynecological conditions. By comparing these two methods, the research seeks to provide insights into the safest and most effective surgical approach.

Who should consider this trial

Good fit: Ideal candidates are women aged 40 to 80 with conditions such as chronic pelvic inflammatory disease, dysfunctional uterine bleeding, or benign ovarian cysts who require laparoscopic hysterectomy.

Not a fit: Patients with known malignancy will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and enhanced sexual function for women undergoing hysterectomy.

How similar studies have performed: Previous studies have shown varying success with laparoscopic approaches, but this specific comparison of closure techniques is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients who undergo laparoscopic hysterectomy
2. Age ranged from 40 to 80 years.
3. Patients suffering from chronic pelvic inflammatory disease (PID)
4. Dysfunctional uterine bleeding
5. Adenomyosis
6. Endometriosis
7. Fibroid
8. Endometrial hyperplasia
9. Benign ovarian cyst

Exclusion Criteria:

* Patients with known malignancy

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Vaginal Vault ProlapseLaparoscopic hysterectomyVaginal hysterectomy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.