Comparing laparoscopic and robotic adrenal surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares laparoscopic and robotic lateral transabdominal adrenalectomy to evaluate patient outcomes and surgeon efficiency. Both procedures are standard care for adrenal tumors, but there is limited comparative data available. The research aims to provide insights that could enhance patient care and optimize resource utilization in adrenal surgery. By analyzing the effectiveness and safety of each approach, the study seeks to inform best practices in surgical techniques.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Men and women between ages 18 and 75
2. Diagnosis of an adrenal tumor/pathology planned for a minimally invasive adrenalectomy at the department of endocrine surgery at the Cleveland Clinic.

Exclusion Criteria:

1. Requirement for an open adrenalectomy based on imaging studies suggesting an aggressive cancer.
2. The presence of extensive surgical history precluding a minimally invasive approach to be undertaken.
3. Patients planned for a partial, rather than a complete adrenalectomy, as the former is a much easier procedure.
4. Patients planned for a posterior adrenalectomy (these would be patients with an extensive surgical history with significant intra-abdominal adhesions and those requiring bilateral adrenalectomy).
5. Mental incapacity or language barrier
6. Any condition, unwillingness, or inability, not covered by any of the other exclusion criteria, which, in the study clinician's opinion, might jeopardize the subject's safety or compliance with the protocol

Where it's running

• The Cleveland Clinic Foundation
  Cleveland, Ohio, United States Recruiting

Study contacts

• Principal investigator: Eren Berber, MD — The Cleveland Clinic
• Study coordinator: Kimberly Jenkins
• Email: jenkink@ccf.org
• Phone: 216 445-4791

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Robotic adrenalectomy with imaging to guide dissection using a dye

  A randomized comparison tests whether adding indocyanine green (ICG) imaging during robotic adrenalectomy helps surgeons find the adrenal gland and perform the operation.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT07813247

• Tirzepatide after adrenalectomy for MACS

  This study tests whether adding tirzepatide after adrenalectomy helps control blood pressure and improve metabolic health in adults with mild autonomous cortisol secretion.

  Recruiting Phase 2 University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07573163

• Radiofrequency Ablation vs Adrenalectomy for unilateral aldosterone-producing adenoma with hypertension

  This study tests whether radiofrequency ablation can match adrenalectomy in treating unilateral aldosterone-producing adenoma causing high blood pressure.

  Recruiting University Hospital, Toulouse · Toulouse · NCT07470580

• Adrenal vein sampling in China

  This project tests whether different adrenal venous sampling techniques and AVS-guided management help people with primary aldosteronism get better long-term blood pressure and hormone results.

  Recruiting at 76 sites Chinese Academy of Medical Sciences, Fuwai Hospital · Hefei, Anhui and 75 other locations · NCT07252284

• Using Gallium-68 Pentixafor PET-CT to improve surgery outcomes in primary aldosteronism

  This trial will test whether adding gallium-68 pentixafor PET/CT to standard adrenal venous sampling helps people with primary aldosteronism have better results from adrenal surgery.

  Recruiting at 2 sites Seoul National University Hospital · Seoul, Gangnam-gu and 1 other locations · NCT07027254

• Omitting preoperative alpha-blockade for normotensive pheochromocytoma

  This study is testing whether skipping a common medication before surgery can help patients with certain tumors avoid low blood pressure during and after their operation without putting them at risk.

  Recruiting Phase 4 Seoul National University Hospital · Seoul · NCT05702944

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.