Comparing kanuka oil and hydrocortisone cream for treating atopic dermatitis

Efficacy of 3% Kanuka Oil Versus 1% Hydrocortisone Cream in the Treatment of Patients With Mild Atopic Dermatitis

Not applicable Interventional Nexgen Dermatologics, Inc. · NCT06488742

This study tests whether 3% kanuka oil can help people with atopic dermatitis feel less itchy and improve their skin better than 1% hydrocortisone cream.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages12 Years to 75 Years
SexAll
SponsorNexgen Dermatologics, Inc. Industry-sponsored
Locations1 site (Boynton Beach, Florida)
Trial IDNCT06488742 on ClinicalTrials.gov

What this trial studies

This study investigates the efficacy of 3% kanuka oil compared to 1% hydrocortisone cream in patients suffering from atopic dermatitis. The focus is on alleviating pruritus, a common and distressing symptom associated with this condition. Participants will be assessed based on their itch severity and overall skin condition to determine which treatment provides better relief. The study aims to explore alternative, natural treatment options for patients who have not found sufficient relief from conventional therapies.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 12 years and older who have been diagnosed with atopic dermatitis for more than two years and experience significant itching.

Not a fit: Patients currently using topical or systemic corticosteroids or other non-emollient therapies may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a natural and effective treatment option for patients with atopic dermatitis, potentially improving their quality of life.

How similar studies have performed: While there are various treatments for atopic dermatitis, the use of kanuka oil is relatively novel, and this study aims to explore its effectiveness compared to a standard treatment.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age greater than 12 years, diagnosis of atopic dermatitis for longer than 2 years, investigator's static global assessment score of either 2 or 3, and initial worst itch numerical rating scale (WI-NRS) for itch greater than 4.

Exclusion Criteria:

* the use of topical or systemic corticosteroids within 28 days of entering the study, the use of any other non-emollient therapy within 28 days of entering the study,nursing, and pregnancy

Where this trial is running

Boynton Beach, Florida

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Dermatitis, AtopicPruritus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.