Comparing IV and oral antibiotics after gallbladder surgery
The Role of Postoperative Antibiotics in Laparoscopic Cholecystectomy
This study tests whether giving antibiotics through an IV or by mouth is better at preventing infections after gallbladder surgery for adults.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Minia University Hospital Academic / other |
| Locations | 1 site (Minya) |
| Trial ID | NCT06607887 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of intravenous versus oral antibiotics in preventing infections following laparoscopic cholecystectomy. It aims to determine which method is more effective in reducing the incidence of postoperative infections. Adult patients undergoing this surgery will be randomly assigned to receive either type of antibiotic treatment. The study will monitor infection rates to assess the outcomes of each approach.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old scheduled for laparoscopic cholecystectomy.
Not a fit: Patients with comorbidities such as diabetes, malignancies, or those who are immunosuppressed may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved infection prevention strategies for patients undergoing gallbladder surgery.
How similar studies have performed: Previous studies have shown varying success with antibiotic prophylaxis in surgical settings, but this specific comparison is less commonly tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients (aged above 18 years) undergoing laparoscopic cholecystectomy. Exclusion Criteria: * patients with comorbidities (Diabetes, malignancies, Immunosuppressed). Lost of follow-up. Patients received antibiotics within 72 hr before admission. Complicated cases involved, gangrenous and perforated cholecystitis and abscess.
Where this trial is running
Minya
- Minia University Hospital — Minya, Egypt (Recruiting)
Study contacts
- Principal investigator: Asmaa A Elsayed, Ph.D. — Sohag University
- Study coordinator: Asmaa A Elsayed
- Email: asmaa.abdelfattah@pharm.sohag.edu.eg
- Phone: 01095727201
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.