Comparing intravenous lidocaine and ketamine for fibromyalgia pain management
Potential Role of Intravenous Lidocaine Versus Intravenous Ketamine for Pain Management in Fibromyalgia Patients
This study tests whether intravenous lidocaine or ketamine can help adults with fibromyalgia who haven't found relief from other treatments manage their pain better.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 75 (estimated) |
| Ages | 25 Years to 50 Years |
| Sex | All |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06184958 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of intravenous lidocaine compared to intravenous ketamine in managing pain for adults with fibromyalgia who have not found relief from standard treatments. Participants aged 25 to 50 years will undergo a thorough medical evaluation, including pain assessments and quality of life questionnaires, before and after receiving the study medications. The study will utilize a randomized, controlled design to minimize bias and ensure reliable results.
Who should consider this trial
Good fit: Ideal candidates are adults aged 25 to 50 with a diagnosis of fibromyalgia and ongoing pain despite maximum medical treatment.
Not a fit: Patients with known hypersensitivity to lidocaine or ketamine, arrhythmias, or who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide new pain management options for fibromyalgia patients who currently experience uncontrolled pain.
How similar studies have performed: Other studies have explored the use of ketamine for pain management, but the direct comparison with lidocaine in fibromyalgia patients is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with FM, diagnosed according to the American College of Rheumatology (ACR) 2016 diagnostic criteria for FM. (Wolfe, F., Clauw, D. J., Fitzcharles, M. A., et al., 2016) Exclusion Criteria: * - Known hypersensitivity to any of the given drugs or one of their derivatives (lidocaine or ketamine). * Known Arrhythmia (Supraventricular or ventricular). * Pregnant females.
Where this trial is running
Cairo
- maha sadek El Derh — Cairo, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.