Comparing intralesional acyclovir and cryotherapy for treating plantar warts
Intralesional Acyclovir Versus Cryotherapy in the Treatment of Plantar Warts. A Randomized Controlled Trial.
This study tests whether a new treatment using acyclovir is safer and works better than the usual freezing method for people with plantar warts.
Quick facts
| Phase | Phase2; Phase3 |
|---|---|
| Study type | Interventional |
| Enrollment | 92 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06261684 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the safety and effectiveness of intralesional acyclovir compared to cryotherapy in treating plantar warts. It is a randomized controlled trial involving patients aged 18 and older who have plantar warts. The study will assess whether intralesional acyclovir is a safer and more effective treatment option than the traditional cryotherapy method. Participants will be monitored for treatment outcomes and any adverse effects.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older with plantar warts.
Not a fit: Patients who are immunocompromised, pregnant, or have had recent treatments for warts may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a new, effective treatment option for patients suffering from plantar warts.
How similar studies have performed: While there have been studies on cryotherapy for plantar warts, the use of intralesional acyclovir is a novel approach that has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18 years or older, of both genders, with plantar warts Exclusion Criteria: * Patients on systemic treatment for warts eg. Acitretin, Acyclovir * Hypersensitivity to Acyclovir * Previous treatment to the same wart during the last 3 months * Immunocompromised patients (as HIV, steroid intake, uncontrolled diabetes, etc.) * Pregnant and breastfeeding females * Cognitively impaired patients
Where this trial is running
Cairo
- Cairo University Hospital — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Basant Helal, MRCP
- Email: basant_helal@hotmail.com
- Phone: +201144166922
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.