Comparing inhalational anesthesia and TIVA for ear surgery
Comparison of Inhalational Anesthesia and Total Intravenous Anesthesia on Surgical Field Quality and Post-operative Recovery in Endoscopic Tympanoplasty
This study is testing whether total intravenous anesthesia (TIVA) leads to less blood loss and better surgical conditions than inhalational anesthesia for patients having ear surgery.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 0 Years to 100 Years |
| Sex | All |
| Sponsor | Our Lady of the Lake Hospital Academic / other |
| Locations | 1 site (Baton Rouge, Louisiana) |
| Trial ID | NCT05993039 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the quality of the surgical field and intraoperative blood loss between inhalational anesthesia and total intravenous anesthesia (TIVA) in patients undergoing endoscopic tympanoplasty. It will be a prospective double-blinded randomized control trial, assessing not only blood loss and surgical field quality but also rates of emergence delirium and total recovery time. The hypothesis is that TIVA will lead to better outcomes compared to inhalational anesthesia in this surgical setting.
Who should consider this trial
Good fit: Ideal candidates are individuals of all ages scheduled for endoscopic tympanoplasty.
Not a fit: Patients with anticoagulation disorders or those currently receiving anticoagulation therapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and recovery times for patients undergoing tympanoplasty.
How similar studies have performed: While TIVA has shown potential advantages in other surgical settings, this specific comparison in endoscopic ear surgery is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals of all ages * Scheduled to undergo an endoscopic tympanoplasty Exclusion Criteria: * Individuals with anticoagulation disorders * Those receiving anticoagulation therapy currently
Where this trial is running
Baton Rouge, Louisiana
- Our Lady of the Lake Hospital — Baton Rouge, Louisiana, United States (Recruiting)
Study contacts
- Principal investigator: Rahul Mehta, MD — Our Lady of the Lake Hospital
- Study coordinator: Leslie S Son, PhD
- Email: Lson@lsuhsc.edu
- Phone: 225-765-7659
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.