Comparing inflammation markers in uterine fluid from normal and scarred uterine cavities

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to investigate the differences in inflammation markers present in fluid aspirated from the uterine cavities of women with intact uteri compared to those who have undergone cesarean sections. Patients will undergo a transvaginal ultrasound to assess uterine integrity, followed by a uterine lavage procedure where sterile saline will be introduced and fluid will be collected for analysis. The collected samples will be snap frozen for immunological analysis to identify potential markers associated with infertility due to nonimplantation and cesarean section complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

- Patients suffering from infertility and assigned for a hydrosonography exam for assessment of the integrity of the uterus and fallopian tubes.

Exclusion Criteria:

1. Patients with hydrosalpinx/pyosalpinx/sactosalpinx
2. Patients who went through surgical correction of a niche
3. Hormonal treatment- estrogens or progestins.
4. Immunosuppressive/immunomodulating medication

Where it's running

• Hadassah Medical Organization
  Jerusalem, Israel Recruiting

Study contacts

• Study coordinator: Chana Adler, MD
• Email: chanaa@hadassah.org.il
• Phone: 972-50-8779068

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.