Comparing infection rates of different dialysis catheters
Comparison of Short-term Application of Dialysis Catheter With Tunnel-cuffed Catheter Versus Non-ccuffed Catheter: a Multicenter Prospective Cohort Study
This study is testing whether using tunnel-cuffed catheters or non-cuffed catheters leads to fewer infections in people receiving hemodialysis.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Beijing Friendship Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing) |
| Trial ID | NCT06206447 on ClinicalTrials.gov |
What this trial studies
This multicenter, prospective cohort study aims to evaluate the short-term infection rates associated with tunnel-cuffed catheters versus non-cuffed catheters in hemodialysis patients. Participants will be divided into two groups based on the type of catheterization used for right internal jugular vein access. The study will compare the incidence of catheter-related infections, thrombosis, and other complications between these two groups to determine which catheter type is more effective in reducing infection rates.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who require immediate hemodialysis and have undergone right internal jugular vein catheterization.
Not a fit: Patients with a history of central venous thrombosis, stenosis, or those on long-term immunosuppression may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved catheter selection, reducing infection rates and complications for hemodialysis patients.
How similar studies have performed: Other studies have shown varying results regarding catheter types, making this investigation relevant but not entirely novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ① Age ≥18 years; ② Uremia, clinical evaluation needs to start hemodialysis immediately, and the right internal jugular vein catheterization is the vascular access for the subjects. ③ Subjects who underwent right internal jugular vein catheterization on regular hemodialysis due to poor internal fistula function and the recovery time of internal fistula was ≥4 weeks; ④ Patients with AKI who need renal replacement therapy and underwent catheterization in the right internal jugular vein, and the renal replacement time is ≥4 weeks. Exclusion Criteria: * ① Subjects with previous history of central venous thrombosis, stenosis, infection, etc. ② The subjects were not dialyzed three times a week; ③ Other subjects with central venous catheterization, including left internal jugular vein, femoral vein and subclavian vein; ④ Those who take immunosuppression for a long time.
Where this trial is running
Beijing, Beijing
- Beijing Friedship Hospital — Beijing, Beijing, China (Recruiting)
Study contacts
- Study coordinator: Wenhu Liu
- Email: wenhuliu@mail.ccmu.edu.cn
- Phone: 15110124629
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.