Comparing individuals with gender dysphoria to a control group
Official title: Comparative Study of Gender Dysphoria Phenomenology and Neurophysiology: Clinical and Experimental Exploration of Gender Identity Disorder
Run by Centre Hospitalier Henri Laborit · NCT04935164 · Data updated 2026-11-12
This study looks at the experiences and brain connections of people with gender dysphoria compared to others to see how their feelings about their gender affect their mood and self-awareness.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | Centre Hospitalier Henri Laborit Academic / other |
| Locations | 1 site (Poitiers) |
| Status | Recruiting |
| Started | March 26, 2021 |
| Main results expected | March 2029 |
| Study ends | December 2029 |
| Registry record updated | October 23, 2026 |
| Trial ID | NCT04935164 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults diagnosed with gender dysphoria who are not currently undergoing psychotropic treatment, hormone therapy, or sexual reassignment surgery.
✕Probably not a fit
Patients with concurrent depression or addiction issues may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the experiences and brain connectivity of individuals diagnosed with gender dysphoria compared to a control group. It focuses on understanding the internal conflict between biological sex and gender identity, and how this may affect mood and self-awareness. Participants will undergo psychiatric evaluations to assess their mental health status and the impact of their condition. The study seeks to gather data that could enhance the understanding of gender dysphoria and its neurological underpinnings.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment approaches and better quality of life for individuals with gender dysphoria.
How similar studies have gone: While there have been studies on gender dysphoria, this specific approach focusing on brain connectivity and self-awareness is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with gender dysphoria * Without psychotropic * Without hormono-therapy * Without sexual surgery assignation Exclusion Criteria: * Any depression * Any addiction
Where it's running
-
Centre Hospitalier Henri Laborit
Poitiers, France Recruiting
Study contacts
- Study coordinator: Bérangère Thirioux, PhD
- Email: berangere.thirioux@ch-poitiers.fr
- Phone: 0033 5 49 44 58 56
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.