Clinical trial Recruiting at 1 site Interventional Ages 18 to 100

Comparing immediate effects of intense cycling, running, and functional strength workouts

Official title: Evaluation of the Acute Effects of High-intensity Interval Aerobic Training, Moderate- and High-intensity Functional Training, and Moderate-intensity Functional Training

Run by European University Miguel de Cervantes · NCT07180550 · Data updated 2026-11-12

This trial tests how different short, intense workouts—cycling, running, high- and moderate-intensity functional training, and traditional strength sessions—affect heart, breathing, and muscle responses in healthy, active adults.

Quick facts

Study typeInterventional
Ages18 Years to 100 Years
SexAll
Enrollment27 (estimated)
SponsorEuropean University Miguel de Cervantes
Academic / other
Locations1 site (Valladolid, Valladolid)
StatusRecruiting
StartedOctober 12, 2025
Main results expectedJanuary 1, 2027
Study endsJanuary 31, 2027
Registry record updatedMarch 10, 2026
Trial IDNCT07180550 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy adults aged 18 or older who are classified as active on the IPAQ and have at least six months of strength training experience at intensities above 75% of one-repetition maximum.

Probably not a fit

People with recent musculoskeletal injury (within 6 months), recent major surgery (within 3 months), medical conditions that contraindicate exercise, or who are not regularly physically active are unlikely to benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study compares immediate cardiovascular, metabolic, and neuromuscular responses to several exercise modalities: HIIT on a cycle and treadmill, high- and moderate-intensity functional training (HIFT and MIFT), and traditional strength training. Healthy adults who are physically active and have at least six months of heavy strength training experience perform controlled exercise bouts while investigators record oxygen consumption (VO2), heart rate variability, heart rate, and metabolic markers. Each participant completes the different protocols in laboratory visits at the university with standardized warm-ups, rest periods, and data collection during and after exercise to capture acute responses. Results are intended to clarify how time-efficient high-intensity functional and interval formats compare to traditional approaches and to inform exercise recommendations for special populations.

Why it matters

Potential benefit: If successful, the findings could identify time-efficient workout formats that produce strong cardiovascular and metabolic responses and help guide safer, targeted exercise prescriptions.

How similar studies have gone: Prior research shows traditional HIIT (running or cycling) reliably provokes strong cardiovascular and metabolic responses, while high-intensity functional training is newer and less thoroughly studied for acute physiological outcomes.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Be 18 years of age or older.
* Have at least 6 months of experience in strength training with intensities greater than 75% of one maximum repetition (1-RM).
* Be classified as active according to the International Physical Activity Questionnaire (IPAQ) score.

Exclusion Criteria:

* Musculoskeletal injury within the 6 months prior to the first visit to the laboratory.
* Recent major surgery (\<3 months).
* Having a medical condition in which physical activity is contraindicated (assessed with the Physical Activity Readiness Questionnaire, PAR-Q+).

Where it's running

  • Miguel de Cervantes European University
    Valladolid, Valladolid, Spain
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.