Comparing immediate dental implants with and without laser treatment after tooth extraction

Comparative Study of Immediate Single Unit Helix GM - Neodent Implants in Early Loading Protocols, With or Without Acqua Surface and With or Without Low Level Laser Photobiomodulation (LLLT). Single-blind Randomized Clinical Trial.

Not applicable Interventional University of Santiago de Compostela · NCT05106855

This study is testing if using laser treatment with immediate dental implants after tooth extraction helps patients heal better and keeps their bone healthy compared to not using lasers.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Santiago de Compostela Academic / other
Locations1 site (Santiago De Compostela, A Coruña)
Trial IDNCT05106855 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of immediate single dental implants placed in fresh alveoli after tooth extraction, comparing protocols that utilize low-level laser photobiomodulation with those that do not. The goal is to assess implant stability and marginal bone loss in patients undergoing oral rehabilitation at the University of Santiago de Compostela. Participants will receive either Grand Morse Acqua or NeoPoros implants, with early loading protocols implemented to enhance recovery and aesthetic outcomes. The study aims to reduce surgical interventions and treatment time while maintaining bone architecture.

Who should consider this trial

Good fit: Ideal candidates include adults requiring tooth extraction with sufficient bone height and space for implant placement, who are not immunosuppressed and smoke fewer than 5 cigarettes per day.

Not a fit: Patients who are immunosuppressed, smoke more than 5 cigarettes per day, or are completely edentulous may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved outcomes in dental implant procedures, reducing recovery time and enhancing aesthetic results for patients.

How similar studies have performed: Other studies have shown promising results with immediate dental implants and photobiomodulation, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients satisfying all inclusion criteria and none of the exclusion criteria will be informed verbally and in writing about the study and signed the informed consent form.
* The implant area is free of infection
* Patients without systemic pathology or medical and general contraindications that are absolute contraindications for surgical procedures;
* Adults who agree to take part in the study and signed the informed consent form.
* Smokers of less than 5 cigarettes/day.
* Not to be completely edentulous.
* Need for extraction of at least one tooth.
* Post-extraction bone area (fresh alveolus).
* Patients with sufficient bone height to obtain primary stability for implant installation (2 mm longer than the largest root).
* Edentulous areas with sufficient mesial-distal, buccolingual and interocclusal space for the placement of an anatomical restoration with a prosthetic space of at least 5 mm.

Exclusion Criteria:

* Immunosuppressed.
* Smokers of more than 5 cigarettes/day.
* Bleeding rate greater than 30 %.
* Presence of active or uncontrolled periodontal disease;
* Patients with less than 2 mm of keratinised gingiva.
* Implants with primary stability with ISQ \< 50
* When this is not possible, assume a security margin to the inferior dental nerve of at least 1 mm.
* Previus history of local radiotherapy in the head and neck region.

Where this trial is running

Santiago De Compostela, A Coruña

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Dental ImplantTooth AbsenceTooth Extractionimmediate implantpost-extraction implantearly loadingphotobiomodulationoral rehabilitation
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.