Comparing immediate and delayed weight bearing after surgery for diabetic ankle fractures

Immediate Vs. Delayed Weight Bearing Postoperative Protocol in Diabetic Ankle Fractures

Not applicable Interventional University of Missouri-Columbia · NCT03966027

This study tests whether letting people with diabetic ankle fractures walk right away after surgery, using a special brace, helps them recover better than waiting to bear weight.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment25 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Missouri-Columbia Academic / other
Locations1 site (Columbia, Missouri)
Trial IDNCT03966027 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of immediate versus delayed weight bearing protocols in patients with diabetic ankle fractures following surgical intervention. It aims to determine whether immediate weight bearing with a hindfoot offloading brace can maintain adequate motion and reduce complications compared to traditional delayed weight bearing methods. The study will enroll up to 25 adult patients who have experienced isolated ankle fractures and will undergo surgery within three weeks of injury. Participants will be monitored for outcome scores and patient satisfaction post-surgery.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 with diabetes who have sustained an isolated ankle fracture and can comply with the postoperative protocol.

Not a fit: Patients who may not benefit include children, pregnant individuals, and those with multiple extremity injuries or chronic ankle fractures requiring surgery beyond three weeks.

Why it matters

Potential benefit: If successful, this approach could improve recovery outcomes and patient satisfaction for individuals with diabetic ankle fractures.

How similar studies have performed: While similar studies have explored weight bearing protocols, this specific approach in diabetic patients is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Adults 18 and ove
2. Positive for diabetes
3. Positive monofilament test
4. Isolated ankle fracture (non-pilon) and undergoing operative intervention within 3 weeks of fracture
5. Weight less than 275 (124kg)
6. Can tolerate and comply with brace
7. No signs of pre-existing charcot arthroplasty or ankle deformity

Exclusion Criteria:

1. Children
2. Pregnant patients
3. No signs of diabetes complicated by neuropathy
4. Non-operative ankle fractures
5. Multiple extremity injury
6. Cannot follow post-operative protocol
7. Chronic ankle fractures receiving surgery beyond 3 weeks of injury

Where this trial is running

Columbia, Missouri

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Ankle FracturesDiabetic Ankle Fractures
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.