Comparing imaging techniques for predicting desmoid tumor progression after cryoablation
Confronto Tra Radiomica e i Criteri Convenzionali di Risposta Nella Previsione Della Progressione Del Tumore Desmoide Dopo Crioablazione
Istituto Ortopedico Rizzoli · NCT06224283
This study is testing if a new imaging method can better predict how desmoid tumors change after cryoablation treatment compared to standard methods.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 21 (estimated) |
| Sex | All |
| Sponsor | Istituto Ortopedico Rizzoli (other) |
| Locations | 1 site (Bologna) |
| Trial ID | NCT06224283 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the effectiveness of radiomics compared to conventional response criteria in predicting the progression of desmoid tumors following cryoablation treatment. Desmoid tumors, while benign, can be locally aggressive and cause significant discomfort. The study involves patients who have undergone cryoablation at the Rizzoli Orthopaedic Institute, with follow-up MRI assessments to monitor changes in tumor heterogeneity over time. The goal is to identify early indicators of tumor response that may not be captured by traditional size-based criteria.
Who should consider this trial
Good fit: Ideal candidates include patients with desmoid tumors who have received cryoablation treatment and have undergone baseline MRI.
Not a fit: Patients who do not have desmoid tumors or have not undergone cryoablation will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved monitoring and management strategies for patients with desmoid tumors, enhancing treatment outcomes.
How similar studies have performed: Other studies have shown promise in using advanced imaging techniques for tumor assessment, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * desmoid tumor treated at Rizzoli Orthopaedic Institute with cryoablation * baseline MRI * clinical and radiologic follow-up until disease progression or the start of a new line of treatment performed every 3 months, with a minimum of 6 months follow-up Exclusion Criteria: \- not meeting inclusion criteria
Where this trial is running
Bologna
- Giancarlo Facchini — Bologna, Italy (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Desmoid