Comparing high flow nasal cannula and conventional oxygen therapy for patients with obstructive sleep apnea after surgery
Comparative Study Between High Flow Nasal Cannula and Conventional Oxygen Therapy in the Postoperative Management of Patients With Mild to Moderate Obstructive Sleep Apnea
This study is testing if high-flow nasal cannula therapy can help patients with obstructive sleep apnea breathe better after surgery compared to regular oxygen therapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 21 Years to 40 Years |
| Sex | All |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06306651 on ClinicalTrials.gov |
What this trial studies
This study compares the effectiveness of high-flow nasal cannula therapy and conventional oxygen therapy in managing oxygen saturation levels in postoperative patients with mild to moderate obstructive sleep apnea. It focuses on measuring the oxygen desaturation index, length of ICU stay, and the need for supplemental CPAP support. The study aims to determine if high-flow nasal cannula therapy can provide a more comfortable and effective alternative to CPAP for patients who are non-adherent. The research is conducted in the postoperative ICU setting, where patients are at risk for complications due to their condition.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 21 to 40 with mild to moderate obstructive sleep apnea undergoing elective non-cardiac surgeries.
Not a fit: Patients with severe obstructive sleep apnea, those dependent on home ventilation, or those with significant comorbidities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve postoperative care and outcomes for patients with obstructive sleep apnea by providing a more effective and comfortable oxygen therapy option.
How similar studies have performed: While there is existing evidence supporting the use of CPAP, the effectiveness of high-flow nasal cannula therapy in this specific postoperative context is less established, making this a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age group from 21 - 40 years old. * Both sexes. * Mild to moderate obstructive sleep apnea (OSA) patients with STOP-BANG score less than 5. * OSA patients undergoing non cardiac surgeries. * Patients who will undergo scheduled elective surgeries under general anesthesia. Exclusion Criteria: * Patient refusal of procedure or participation in the study. * Patients with severe OSA, STOP-BANG score more than or equal 5. * Patients dependent on home ventilation CPAP or bilevel devices. * Pregnant females. * Post cardiac or thoracic surgery patients. * More than American Society of Anesthesiologists (ASA) II patients. * Head and face trauma patients.
Where this trial is running
Cairo
- Ain Shams University — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Omar M Mohamed, Master
- Email: omarmedhat0100565@med.asu.edu.eg
- Phone: 00201063190923
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.