Comparing high and low power settings for laser treatment of kidney stones
High Versus Low Power Settings During Ureteroscopic Laser Lithotripsy - a Prospective, Randomised Clinical Trial
This study is testing whether using high or low power settings during laser treatment can help people with kidney stones get better results and have fewer complications.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Haukeland University Hospital Academic / other |
| Locations | 1 site (Bergen, Vestland) |
| Trial ID | NCT05697250 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the effectiveness of high versus low power settings during ureteroscopic laser lithotripsy for patients with renal stones. Patients aged 18 and older with stones measuring 8-25 mm will be randomly assigned to receive treatment using either low power settings (4-6 Watts) or high power settings (16-18 Watts) of a Thulium Fiber Laser. The primary outcome measured will be the operative time, while secondary outcomes will include stone-free rates, laser activation patterns, and complication rates. Follow-up will involve a low dose CT scan three months post-procedure to assess the success of the treatment.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older scheduled for ureteroscopic lithotripsy for renal stones sized between 8-25 mm.
Not a fit: Patients with concomitant ureteral stones, urinary diversion, active infections, or untreated cancer in the upper urinary tract may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to optimized laser settings that improve treatment efficiency and patient outcomes in kidney stone removal.
How similar studies have performed: While previous studies have shown the Thulium Fiber Laser to be effective, this specific comparison of high versus low power settings is novel and has not been tested in clinical trials.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients ≥ 18 years scheduled for URS lithotripsy for renal stones, 8-25 mm, at the day surgery unit at Haukeland University Hospital Exclusion Criteria: * Concomitant ureteral stone * Urinary diversion * Active infection * Untreated cancer in the upper urinary tract
Where this trial is running
Bergen, Vestland
- Haukeland University Hospital — Bergen, Vestland, Norway (Recruiting)
Study contacts
- Principal investigator: Øyvind Ulvik, Assoc Prof — Haukeland University Hospital
- Study coordinator: Øyvind Ulvik, Assoc Prof
- Email: doc.ulvik@online.no
- Phone: +47 90918595
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.