Comparing heparin solution and barrier gel for preventing intrauterine adhesions after surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of heparin solution versus hyaluronic acid barrier gel in preventing intrauterine adhesions following operative hysteroscopy. Patients undergoing this procedure will receive either treatment immediately after surgery, and their outcomes will be assessed through follow-up hysteroscopy 4 to 8 weeks later. The study will measure the incidence and severity of adhesions, as well as any changes in menstrual patterns and fertility over the following year. Data collected will help determine which method is more effective in reducing post-surgical complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* female sex
* indication for operative hysteroscopy including one or more of the following:
* infertility,
* irregular bleeding,
* oligo-/amenorrhea,
* Asherman syndrome,
* G0-G3 fibroids,
* dysmorphic uterus.

Exclusion Criteria:

* ongoing pregnancy,
* genital cancer,
* pelvic inflammatory disease,
* excessive uterine bleeding.

Where it's running

• Nadezhda Women's Health Hospital
  Sofia, Sofia, Bulgaria Recruiting
• Nadezhda Women's Health Hospital
  Sofia, Bulgaria Recruiting

Study contacts

• Study coordinator: Georgi Stamenov
• Email: g.stamenov1@abv.bg
• Phone: +359888269839

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Intrauterine Adhesion Prevention With a Uterine Stent After Surgery

  This trial tests whether placing a uterine stent after adhesion surgery helps prevent repeat adhesions in women aged 20–40 with intrauterine adhesions.

  Recruiting The Third Xiangya Hospital of Central South University · Changsha, Hunan · NCT07611474

• A combined 4D ultrasound, hysteroscopic cold-knife plowing, uterine stent, and traditional Chinese medicine approach for intrauterine adhesions

  This project will try a combined care pathway—preoperative 4D ultrasound, hysteroscopic cold-knife adhesion separation, a postoperative uterine stent, and traditional Chinese medicine—to see if it improves outcomes for women aged 18–45 with intrauterine adhesions.

  Recruiting The Third Xiangya Hospital of Central South University · Changsha, Hunan · NCT07421908

• Intrauterine Stent Placement After Septum Resection

  This trial tests whether placing a small intrauterine balloon stent for 7-10 days after hysteroscopic septum removal helps prevent scar tissue formation in people with a uterine septum.

  Recruiting Weill Medical College of Cornell University · Little Rock, Arkansas and 2 other locations · NCT07032506

• Using Platelet-rich Plasma to Improve Female Fertility

  This study is testing whether injections of platelet-rich plasma can help improve fertility in women dealing with issues like poor ovarian response and repeated implantation failure.

  Recruiting The Fourth Affiliated Hospital of Zhejiang University School of Medicine · Yiwu, Zhejiang · NCT06645379

• Comparison of operative hysteroscopy vs vacuum aspiration for first-trimester termination with intrauterine adhesions

  In people with early pregnancy and intrauterine adhesions, this study tests whether hysteroscopy with adhesiolysis plus vacuum aspiration is safer or more effective than vacuum aspiration alone for terminating the pregnancy.

  Recruiting Women's Hospital School Of Medicine Zhejiang University · Hangzhou · NCT07883057

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.