Comparing genicular nerve block and physical therapy for knee osteoarthritis
Comparison of the Effects of Ultrasound-guided Genicular Nerve Block and Conventional Physical Therapy on Pain, Functionality and Balance in Patients With Knee Osteoarthritis
This study is testing whether a genicular nerve block or physical therapy works better to relieve pain and improve movement for people with knee osteoarthritis.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 66 (estimated) |
| Ages | 40 Years to 70 Years |
| Sex | All |
| Sponsor | Ahi Evran University Education and Research Hospital Academic / other |
| Drugs / interventions | radiation |
| Locations | 2 sites (Kirşehi̇r, Kirşehi̇r and 1 other locations) |
| Trial ID | NCT06903936 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of genicular nerve block (GNB) compared to physical therapy (PT) in treating patients with knee osteoarthritis (KOA). It aims to relieve pain and improve function through non-surgical interventions. Participants will be divided into three groups: those receiving GNB, those undergoing PT, and those participating in an exercise program. The study will assess outcomes related to pain relief, functional improvement, and quality of life over a specified period.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 40 to 70 with radiological evidence of moderate knee osteoarthritis and chronic knee pain.
Not a fit: Patients with recent treatments for knee osteoarthritis or those with certain medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide patients with effective non-surgical treatment options for managing knee osteoarthritis.
How similar studies have performed: Previous studies have shown promising results for both genicular nerve blocks and physical therapy in treating knee osteoarthritis, indicating that this approach is supported by existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
INCLUSION CRITERIA * Being between forty and seventy years old * Kellgren-Lawrence grade two-thee radiological osteoarthritis * Knee pain for at least three months * Those who consented to participate in the study according to the informed consent form EXCLUSION CRITERIA * Pregnancy * Malignancy * Epilepsy * History of cardiac pacemaker * Those who have received glucocorticosteriod, hyaluronic acid, PRP, Genicular block injection in the last six months * Those who received physical therapy in the last six months * Those taking oral glucosamine in the last six months * Anticoagulant use * History of systemic inflammatory disease * History of fracture and surgery in the lower extremity * Open wounds on the knees * History of systemic infection in the patient * Inability of the patient to cooperate * History of neuromuscular disease affecting balance parameters * Patient's unwillingness to participate in the study
Where this trial is running
Kirşehi̇r, Kirşehi̇r and 1 other locations
- Kirsehir Ahi Evran University Physical Medicine and Rehabilitation Hospital — Kirşehi̇r, Kirşehi̇r, Turkey (Türkiye) (Recruiting)
- Ahi Evran University Hospital — Kırşehir, Kırşehir, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: Hacer I Altay Caglar, ra — Kirsehir Ahi Evran University Physical Medicine and Rehabilitation Hospital
- Study coordinator: Hacer I Altay Caglar, ra
- Email: iremela.7@gmail.com
- Phone: +905456555428
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.