Comparing General and Spinal Anesthesia Effects on Heart Injury After Hip Surgery
Comparison of The Effects of General Anesthesia and Spinal Anesthesia on The Development of Postoperative Myocardial Injury in Elderly Patients Undergoing Hip Surgery
This study is testing whether general anesthesia or spinal anesthesia causes less heart injury in older patients after hip surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Sisli Hamidiye Etfal Training and Research Hospital Academic / other |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT06343259 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the effects of general anesthesia versus spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery. It is a prospective, randomized, single-blind study that focuses on myocardial injury after non-cardiac surgery (MINS), which is characterized by asymptomatic troponin elevation. The study will monitor troponin levels from the preoperative period up to 72 hours post-surgery to assess the impact of the type of anesthesia on cardiovascular outcomes. Given the rising number of elderly patients with comorbidities undergoing such surgeries, understanding these effects is crucial for improving postoperative care.
Who should consider this trial
Good fit: Ideal candidates for this study are elderly patients over the age of 65 who are scheduled to undergo hip surgery and have an ASA classification of II-III.
Not a fit: Patients with severe comorbidities such as sepsis, pulmonary embolism, or chronic kidney failure, or those with recent cardiac events, will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved anesthesia practices that reduce the risk of myocardial injury in elderly patients after surgery.
How similar studies have performed: Previous studies have indicated a significant prevalence of MINS in similar patient populations, suggesting that this approach could yield valuable insights into anesthesia practices.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * who will undergo hip surgery * ASAII-III * Over the age of 65 Exclusion Criteria: * Patients diagnosed with sepsis, pulmonary embolism, decompensated heart failure, chronic kidney failure. * Patients who underwent cardioversion in the last 6 months or experienced myocardial infarction. * Patients with a surgical history in the last month. * Patients who required intubation in the intensive care unit. * Patients with a baseline Hs-Troponin T value exceeding 20 ng/L. * Patients with a postoperative peak Hs-Troponin T value higher than baseline.
Where this trial is running
Istanbul
- Sisli Hamidiye Etfal Training and Research Hospital — Istanbul, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Mustafa Bilgehan AYIK
- Email: drbilgehanayik@gmail.com
- Phone: +905377247984
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.