Comparing full pulpotomy and root canal treatment for irreversible pulpitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to compare the effectiveness of full pulpotomy versus traditional root canal treatment in adults with symptomatic irreversible pulpitis in their posterior teeth. It will involve a randomized controlled design to assess outcomes related to pain relief and tooth preservation. Additionally, the study will evaluate the cost-effectiveness of pulpotomy and gather feedback from both dentists and patients regarding the acceptability of the treatment options. The trial seeks to provide robust evidence to inform clinical practice in endodontics.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 12 years or older (with a mature permanent tooth demonstrating radiographic evidence of a deep caries/restorations and signs/ symptoms indicative of IRP (moderate to severe spontaneous lingering pain). Tooth will be responsive to cold and EPT sensibility testing, restorable and can be adequately isolated during treatment. One posterior tooth (molar or premolar) only per patient.

Exclusion Criteria:

* Teeth with active periodontal disease (pocket depth \>5mm); teeth indicated for elective root canal treatment for restorative purposes, teeth with apical periodontitis, patients with complex medical histories that may affect their caries experience and healing ability (immunocompromised, radiotherapy), patients who are unable to consent; history of previous trauma to the tooth, presence of apical radiolucency and patients who are pregnant or breast-feeding. Intraoperatively, any evidence of purulence or excessive bleeding that cannot be controlled with a cotton pellet with 2-4% hypochlorite for 10 minutes will be excluded.

Where it's running

• Hany Mohamed Aly Ahmed
  Kuala Lumpur, Malaysia Recruiting

Study contacts

• Principal investigator: Hany Ahmed, PhD — University of Malaya
• Study coordinator: Hany Ahmed, PhD
• Email: hanyendodontist@um.edu.my
• Phone: 0060129857937

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.