Comparing flap closure methods after impacted lower wisdom tooth removal

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized controlled trial that assigns patients to one of four commonly used flap closure techniques following extraction of a similarly positioned impacted mandibular third molar. Outcomes include postoperative pain, facial swelling, trismus (limited mouth opening), wound healing, and patient-reported oral health quality of life (GOHAI) measured at scheduled follow-ups. The four interventions compared are conventional silk suturing, a sutureless approach (secondary intention), placement of a surgical drain, and closure with a high-viscosity cyanoacrylate tissue adhesive. Eligible participants are healthy adults (ASA I) aged 18–40 with specific impaction classifications, and the procedures and follow-ups take place at a single university oral surgery department.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18-40 years.
* Patients with no systemic diseases (ASA I).
* Patients with impacted mandibular third molars indicated for extraction, with bone and/or mucosal retention, in similar positions (Pell \& Gregory Class 2, Position B; Winter classification vertical or mesioangular).

Exclusion Criteria:

* Patients classified as ASA II, III, or IV.
* Known allergy to anesthetic solutions.
* Allergy to acrylate.
* Pregnant or breastfeeding women.
* Individuals with tobacco use ≥10 cigarettes/day.
* Alcohol users.
* Patients using antiplatelet agents.
* Patients using anticoagulants.
* Patients with coagulation disorders.
* Patients with immunosuppressive diseases or receiving immunosuppressive therapy.

Patients with acute pain or local infection at the surgical site.

Where it's running

• Recep Tayyip Erdoğan University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery
  Rize, Rize Province, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Alperen Kalyoncu, Assistant Professor
• Email: alperen.kalyoncu@erdogan.edu.tr
• Phone: +905058261967

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.