Comparing exercise capacity and quality of life in children with primary immunodeficiency and healthy peers
Comparison of Exercise Capacity, Physical Activity Level and Quality of Life of Children With Primary Immunodeficiency With Healthy Children
This study looks at how kids with primary immunodeficiency compare to healthy kids in terms of exercise ability and quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 52 (estimated) |
| Ages | 6 Years to 18 Years |
| Sex | All |
| Sponsor | Gazi University Academic / other |
| Locations | 1 site (Ankara, Çankaya) |
| Trial ID | NCT05999422 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate and compare various health metrics, including maximal exercise capacity, respiratory functions, physical activity levels, and quality of life, between children diagnosed with primary immunodeficiency diseases (PID) and healthy individuals. The study will involve 26 PID patients and 26 age- and sex-matched healthy controls, with statistical analyses performed to identify differences between the two groups. The findings are expected to provide insights into how PID affects physical health and overall quality of life in affected children.
Who should consider this trial
Good fit: Ideal candidates for this study are children aged 6-18 years diagnosed with primary immunodeficiency diseases who are receiving standard medical treatment.
Not a fit: Patients with orthopedic or neurological disorders affecting exercise capacity, or those with acute infections, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of the impact of primary immunodeficiency on children's health and inform better management strategies.
How similar studies have performed: While there is limited data on similar studies specifically focusing on exercise capacity in PID patients, the approach of comparing health metrics with healthy controls has been utilized in other contexts with varying degrees of success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients: * Individuals aged 6-18 years, diagnosed with primary immune deficiency disease and receiving standard medical treatment, will be included in the study. Healthy controls: * Individuals between the ages of 6 and 18 without a known chronic disease will be included. Exclusion Criteria: Patients: * Patients who are uncooperative, have orthopedic or neurological disorders that will affect their exercise capacity, and have pneumonia or any acute infection during the evaluation will be excluded from the study. Healthy controls: * Those with a known chronic disease, uncooperative and orthopedic or neurological disorders that will affect their exercise capacity will not be included.
Where this trial is running
Ankara, Çankaya
- Gazi University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Cardiopulmonary Rehabilitation Unit — Ankara, Çankaya, Turkey (Recruiting)
Study contacts
- Principal investigator: Caner Aytekin, Assoc. Prof — MH. Dr. Sami Ulus Children's Health and Diseases Training and Research Hospital
- Study coordinator: Meral Boşnak Güçlü, Prof.Dr.
- Email: meralbosnak@gazi.edu.tr
- Phone: +903122162647
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.