Comparing exercise capacity and muscle oxygenation in patients with interstitial lung disease and healthy individuals
Official title: Comparison of Exercise Capacity, Muscle Oxygenation and Physical Activity Levels Between Patients With Interstitial Lung Disease and Healthy Individuals
Run by Gazi University · NCT06948942 · Data updated 2026-11-12
This study looks at how exercise and muscle oxygen levels differ between people with interstitial lung disease and healthy individuals to better understand the challenges ILD patients face in staying active.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Gazi University Academic / other |
| Locations | 1 site (Ankara) |
| Status | Recruiting |
| Started | December 12, 2024 |
| Main results expected | July 12, 2025 |
| Study ends | September 12, 2025 |
| Registry record updated | April 29, 2025 |
| Trial ID | NCT06948942 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 to 75 diagnosed with interstitial lung disease according to ATS/ERS criteria.
✕Probably not a fit
Patients with acute pulmonary exacerbations, obstructive lung disease, or serious cardiovascular conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to compare the exercise capacity, muscle oxygenation, and physical activity levels between patients diagnosed with interstitial lung disease (ILD) and healthy individuals. It will assess various factors including respiratory functions, muscle strength, and quality of life to understand the impact of ILD on physical activity. By identifying differences in these parameters, the study seeks to highlight the challenges faced by ILD patients in maintaining an active lifestyle. The findings could provide insights into the management and rehabilitation of individuals with ILD.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management strategies for patients with interstitial lung disease, enhancing their quality of life.
How similar studies have gone: While there are studies comparing different lung disease groups with healthy individuals, this specific comparison of exercise capacity and muscle oxygenation in ILD has not been previously conducted.
Who can join: the full rules
Show full inclusion / exclusion criteria
Patients who will participate in the study; Inclusion Criteria: * Patients diagnosed with ILD according to ATS/ERS criteria, * Ages between 18 and 75, * Pulmonary infection during the previous month, * Participants who voluntarily participated in the study were included. Exclusion Criteria: * Patients were excluded if they had: * Acute pulmonary exacerbation or respiratory infection in the last four weeks * Obstructive lung disease * Systemic conditions affecting neurological, neuromuscular, orthopedic, or physical functions * Recent participation in a planned exercise program (within three months) * Cognitive impairment affecting exercise test understanding * Contraindications to exercise testing per the American Sports Medicine Association * Cancer, renal, or hepatic disease * Aortic stenosis, complex arrhythmia, or aortic aneurysm * Serious cardiovascular diseases like uncontrolled hypertension, diabetes, heart failure, or arrhythmia For healthy individuals who will participate in the study; Inclusion Criteria: * No diagnosed chronic disease, * Healthy adults between the ages of 45-80 Exclusion Criteria: * Individuals with a Mini Mental State Assessment Scale score of less than 24, * A smoking history of at least 10 packs×years or more, * Having had COVID-19, * A BMI of \>30 kg/m2
Where it's running
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Gazi University Faculty of Health Sciences Department of Physiotherapy and Rehabilitation, Cardiopulmonary Rehabilitation Unit
Ankara, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Nazire Nur YILDIZ, M.Sc. — Nigde Omer Halisdemir University
- Study coordinator: Meral BOŞNAK GÜÇLÜ, Prof. Dr.
- Email: meralbosnak@gazi.edu.tr
- Phone: +903122162647
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.