Comparing exercise capacity and muscle oxygenation in patients with interstitial lung disease and healthy individuals

Comparison of Exercise Capacity, Muscle Oxygenation and Physical Activity Levels Between Patients With Interstitial Lung Disease and Healthy Individuals

This study looks at how exercise and muscle oxygen levels differ between people with interstitial lung disease and healthy individuals to better understand the challenges ILD patients face in staying active.

Quick facts

• Study type: Observational
• Enrollment: 40 (estimated)
• Ages: 18 Years to 75 Years
• Sex: All
• Sponsor: Gazi University (other)
• Locations: 1 site (Ankara)
• Trial ID: NCT06948942 on ClinicalTrials.gov

What this trial studies

This observational study aims to compare the exercise capacity, muscle oxygenation, and physical activity levels between patients diagnosed with interstitial lung disease (ILD) and healthy individuals. It will assess various factors including respiratory functions, muscle strength, and quality of life to understand the impact of ILD on physical activity. By identifying differences in these parameters, the study seeks to highlight the challenges faced by ILD patients in maintaining an active lifestyle. The findings could provide insights into the management and rehabilitation of individuals with ILD.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 to 75 diagnosed with interstitial lung disease according to ATS/ERS criteria.

Not a fit: Patients with acute pulmonary exacerbations, obstructive lung disease, or serious cardiovascular conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management strategies for patients with interstitial lung disease, enhancing their quality of life.

How similar studies have performed: While there are studies comparing different lung disease groups with healthy individuals, this specific comparison of exercise capacity and muscle oxygenation in ILD has not been previously conducted.

Eligibility criteria

Patients who will participate in the study;

Inclusion Criteria:

* Patients diagnosed with ILD according to ATS/ERS criteria,
* Ages between 18 and 75,
* Pulmonary infection during the previous month,
* Participants who voluntarily participated in the study were included.

Exclusion Criteria:

* Patients were excluded if they had:
* Acute pulmonary exacerbation or respiratory infection in the last four weeks
* Obstructive lung disease
* Systemic conditions affecting neurological, neuromuscular, orthopedic, or physical functions
* Recent participation in a planned exercise program (within three months)
* Cognitive impairment affecting exercise test understanding
* Contraindications to exercise testing per the American Sports Medicine Association
* Cancer, renal, or hepatic disease
* Aortic stenosis, complex arrhythmia, or aortic aneurysm
* Serious cardiovascular diseases like uncontrolled hypertension, diabetes, heart failure, or arrhythmia

For healthy individuals who will participate in the study;

Inclusion Criteria:

* No diagnosed chronic disease,
* Healthy adults between the ages of 45-80

Exclusion Criteria:

* Individuals with a Mini Mental State Assessment Scale score of less than 24,
* A smoking history of at least 10 packs×years or more,
* Having had COVID-19,
* A BMI of \>30 kg/m2

Where this trial is running

Ankara

• Gazi University Faculty of Health Sciences Department of Physiotherapy and Rehabilitation, Cardiopulmonary Rehabilitation Unit — Ankara, Turkey (Türkiye) (RECRUITING)

Study contacts

• Principal investigator: Nazire Nur YILDIZ, M.Sc. — Nigde Omer Halisdemir University
• Study coordinator: Meral BOŞNAK GÜÇLÜ, Prof. Dr.

Conditions: Interstitial Lung Diseases, Healthy Individuals, Exercise Capacity, Muscle Oxygenation, Physical Activity Level, Interstitial lung diseases, Healthy individuals, Exercise capacity