Comparing Evolutionary Systems Therapy and Cognitive Behavioral Therapy for Schizotypal Personality Disorder
A Confirmatory Randomized Controlled Trial Comparing Evolutionary Systems Therapy for Schizotypal Personality Disorder With Cognitive Behavioral Therapy
This study is testing whether a new therapy called Evolutionary Systems Therapy can help people with Schizotypal Personality Disorder feel better compared to the usual Cognitive Behavioral Therapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 28 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Tages Onlus Academic / other |
| Locations | 1 site (Firenze, FI) |
| Trial ID | NCT05710926 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of Evolutionary Systems Therapy for Schizotypy (ESTS) compared to Cognitive Behavioral Therapy (CBT) in treating Schizotypal Personality Disorder (SPD). A total of 38 patients diagnosed with SPD will be randomly assigned to receive either ESTS or CBT, with the primary focus on reducing general symptoms. Secondary outcomes will assess changes in self-criticism and metacognition, as well as remission from the diagnosis. The study seeks to provide insights into the feasibility and effectiveness of ESTS without the influence of mandatory pharmacological treatment.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 or older diagnosed with Schizotypal Personality Disorder who can participate in therapy conducted in Italian.
Not a fit: Patients with schizophrenia spectrum disorders, other psychotic disorders, neurodevelopmental or neurological disorders, bipolar disorder, or those currently undergoing psychological or pharmacological treatment may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could offer a new therapeutic option for patients with Schizotypal Personality Disorder.
How similar studies have performed: While previous studies have suggested the potential effectiveness of ESTS, this approach is being tested in a new context without mandatory pharmacological treatment, making it a novel investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of Schizotypal Personality Disorder at SCID-5-AMPD Module III * Age 18 or older * Being capable of reading and signing the inform consent form in Italian * Being capable of attending a talk therapy in Italian Exclusion Criteria: * Being diagnosed with schizophrenia spectrum disorders or other psychosis disorder * Being diagnosed with neurodevelopmental or neurological disorders * Being diagnosed with bipolar disorder * Being under any psychological or pharmacological treatment
Where this trial is running
Firenze, FI
- Centro di Psicologia e Psicoterapia Tages Onlus - Firenze — Firenze, Fi, Italy (Recruiting)
Study contacts
- Principal investigator: Simone Cheli, PhD — Tages Onlus
- Study coordinator: Simone Cheli, PhD
- Email: simone.cheli@tagesonlus.org
- Phone: +393285642442
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.