Comparing European and Japanese methods for examining colon cancer

Comparison Between the European and Japanese Pathological Investigation for Colon Cancer (SPACE)

Phase 3 Interventional Russian Society of Colorectal Surgeons · NCT06119867

This study is testing whether the way doctors in Japan check for colon cancer is as accurate as the method used in Europe for patients who have had surgery for colon cancer.

Quick facts

PhasePhase 3
Study typeInterventional
Enrollment430 (estimated)
SexAll
SponsorRussian Society of Colorectal Surgeons Academic / other
Locations1 site (Moscow)
Trial IDNCT06119867 on ClinicalTrials.gov

What this trial studies

This study aims to compare the diagnostic accuracy of the European and Japanese pathological investigation methods for colon cancer. The European approach relies primarily on pathologists without surgical involvement, while the Japanese method includes surgeons in the evaluation process. The study will assess whether the Japanese method is less accurate than the European method, which has not been systematically evaluated in the literature. Patients diagnosed with colon cancer who have undergone colectomy will be included in the trial.

Who should consider this trial

Good fit: Ideal candidates are patients diagnosed with colon cancer who have undergone colectomy and have confirmed adenocarcinoma.

Not a fit: Patients with rectal cancer or those who have not undergone colectomy will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the accuracy of colon cancer diagnoses, leading to better treatment outcomes.

How similar studies have performed: There is limited literature on the Japanese pathological assessment method, making this a novel evaluation.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients diagnosed with colon cancer who underwent colectomy;
* Patients with pathological confirmed adenocarcinoma;
* Patients agreed to participate in the study.

Exclusion Criteria:

* Patients suffered from rectal cancer;
* Patients diagnosed with colon cancer but did not undergo colectomy;
* Patients refused participation.

Where this trial is running

Moscow

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Colonic Neoplasms
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.