Comparing ESWT and Ozone Injection for Chronic Plantar Fasciitis

Comparison of the Efficiency of Extracorporeal Shock Wave Therapy and Ultrasound-Guided Ozone Injection in Patients With Chronic Plantar Fasciitis

Not applicable Interventional Ankara City Hospital Bilkent · NCT06041230

This study is testing whether Extracorporeal Shock Wave Therapy or ozone injections work better for people with chronic heel pain that hasn't improved with other treatments.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment48 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorAnkara City Hospital Bilkent Academic / other
Locations1 site (Ankara)
Trial IDNCT06041230 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of Extracorporeal Shock Wave Therapy (ESWT) versus ozone injections in treating patients with chronic plantar fasciitis. ESWT uses acoustic waves to enhance healing and reduce pain, while ozone injections aim to provide analgesic and anti-inflammatory effects. The study targets individuals who have not responded to conventional treatments for heel pain lasting over three months. Participants will be assessed for pain levels and ultrasound findings to confirm the diagnosis.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 with persistent heel pain for more than three months and specific ultrasound findings indicative of plantar fasciitis.

Not a fit: Patients with inflammatory arthritis, recent heel injuries, or those who have received local injections in the past six months may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could offer patients a more effective treatment option for chronic plantar fasciitis.

How similar studies have performed: Other studies have shown promising results with both ESWT and ozone therapy in treating musculoskeletal disorders, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Be over 18 years old
* Heel pain lasting longer than 3 months
* Localized pain and tenderness on palpation on the medial aspect of the calcaneal tuberosity when the ankle is fully dorsiflexed.
* In the first step of walking, \>50 mm according to VAS. and description of pain
* Presence of plantar fasciitis typical findings on ultrasonography (thickening more than 4 mm in the proximal plantar fascia with changes in fibril pattern)
* Failure to respond to conservative treatment before (nonsteroidal anti-inflammatory drugs, stretching, heel cushion, shoe modifications, orthotics, cold, heat, taping, massage)

Exclusion Criteria:

* being under the age of 18
* Any skin lesions in the heel area
* Inflammatory, rheumatic arthritis
* Having a history of fracture, trauma or operation in the heel area
* Systemic infection or malignancy
* Having a pacemaker
* Local injection to the heel area in the last 6 months or use of topical or oral nonsteroidal anti-inflammatory drugs in the last 2 weeks

Where this trial is running

Ankara

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Plantar Fascitisozone therapyESWT
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.