Comparing effects of two types of bupivacaine in spinal anesthesia for older patients undergoing hip surgery
Comparison of Hemodynamic Effects of Hypobaric and Hyperbaric Bupivacaine in Spinal Anesthesia During Hip Surgery in Geriatric Patients
This study is testing whether two different types of bupivacaine used in spinal anesthesia can provide better stability for older patients during hip surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Eskisehir Osmangazi University Academic / other |
| Locations | 1 site (Eski̇şehi̇r, Odunpazari) |
| Trial ID | NCT06972485 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the hemodynamic effects of hypobaric and hyperbaric bupivacaine in geriatric patients receiving spinal anesthesia for hip surgery. Patients over 65 years old will be randomly assigned to receive either hypobaric or hyperbaric bupivacaine, with hemodynamic parameters monitored throughout the procedure. The study will assess the effectiveness of the spinal anesthesia by measuring sensory and motor block levels, as well as recording vital signs and any intraoperative complications. The goal is to determine which type of bupivacaine provides better hemodynamic stability in this vulnerable population.
Who should consider this trial
Good fit: Ideal candidates are patients over 65 years old undergoing hip surgery who are classified as ASA class I-III.
Not a fit: Patients with a history of drug allergy, coagulopathy, or severe valve stenosis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved anesthesia protocols that minimize hypotension in older patients during hip surgery.
How similar studies have performed: While there have been studies on bupivacaine in anesthesia, this specific comparison of hypobaric versus hyperbaric formulations in geriatric patients is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients over 65 years of age * Patients taken to surgery in a supine position due to femur fractures * Patients classified as ASA (American Society of Anesthesiologists) class I-III Exclusion Criteria: * History of allergy to the drug * Patients with coagulopathy * Patients refusing to participate in the study * Severe valve stenosis * Infection at the injection site * Inadequate spinal anesthesia level during surgery
Where this trial is running
Eski̇şehi̇r, Odunpazari
- Eskişehir Osmangazi University — Eski̇şehi̇r, Odunpazari, Turkey (Recruiting)
Study contacts
- Study coordinator: Fadime A Alagaş, research ass
- Email: drfadimekocak@gmail.com
- Phone: +90 05395299589
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.