Comparing EEG-guided and index-guided anesthesia for brain surgery
Comparisons Between Electroencephalographic Spectrogram-guided and Bispectral Index-guided Multimodal General Anesthesia During Craniotomy- a Randomized Controlled Trial
This study tests whether using brain activity monitoring during anesthesia can help improve the experience and outcomes for patients having brain surgery compared to standard methods.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT06244017 on ClinicalTrials.gov |
What this trial studies
This trial compares the effects of EEG spectrogram-guided anesthesia versus traditional index-guided anesthesia in patients undergoing elective craniotomy. The study utilizes a multimodal approach, combining various anesthetic agents while monitoring brain activity through EEG to optimize drug administration. By using EEG density spectral arrays, the trial aims to provide a more tailored anesthesia experience that accounts for individual patient variations, potentially improving outcomes during surgery.
Who should consider this trial
Good fit: Ideal candidates for this study are patients scheduled for elective craniotomy.
Not a fit: Patients undergoing revision surgery, those with heart failure, liver cirrhosis greater than Child B class, or chronic obstructive pulmonary disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more precise anesthesia management, enhancing patient safety and recovery during craniotomy procedures.
How similar studies have performed: While the use of EEG for anesthesia monitoring is gaining interest, this specific approach comparing EEG spectrogram-guided anesthesia to traditional methods is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients undergoing elective craniotomy Exclusion Criteria: * revision surgery * heart failure * liver cirrhosis \> Child B class * chronic obstructive pulmonary disease
Where this trial is running
Taipei
- National Taiwan University Hospital — Taipei, Taiwan (Recruiting)
Study contacts
- Principal investigator: Chun-Yu Wu — National Taiwan University Hospital Hsinchu Branch
- Study coordinator: Chun-Yu Wu
- Email: b001089018@tmu.edu.tw
- Phone: 886976653376
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.