Comparing Eccentric Training and Conventional Therapy for Stroke Recovery

Characterization of the Neuromuscular and Biomechanical Properties of Spastic Myopathy-affected Muscles During the Generation of Passive and Active Force: the Effect of a Management Program Based on Eccentric Exercises.

Not applicable Interventional Clinique Du Parc de Belleville · NCT06140381

This study is testing if a special type of exercise called eccentric training can help stroke survivors walk faster compared to regular therapy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages20 Years to 75 Years
SexAll
SponsorClinique Du Parc de Belleville Academic / other
Locations1 site (Créteil)
Trial IDNCT06140381 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of eccentric training versus conventional therapy in improving gait speed among sub-acute stroke survivors. Participants will be randomly assigned to either the Eccentric Training Group or the Conventional Therapy Group, with assessments conducted at three key time points: initial, intermediate, and final. The study will include a variety of evaluations, such as clinical health assessments, biomechanical assessments, and functional assessments, over a total duration of eight weeks. The primary focus is on enhancing neuromuscular parameters and muscle stiffness in the affected areas.

Who should consider this trial

Good fit: Ideal candidates are sub-acute stroke survivors with hemiparesis who have a BMI between 18.5 and 25.

Not a fit: Patients with ankle impairments, recent botulinum toxin injections, or significant cardiovascular or neurodegenerative disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved rehabilitation strategies for stroke survivors, enhancing their mobility and quality of life.

How similar studies have performed: Other studies have shown promising results with eccentric training approaches in rehabilitation, suggesting potential for success in this study as well.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subacute hemiparesis (\> 3 months)
* BMI between 18.5 and 25
* Written consent to participate in the study.

Exclusion Criteria:

* Ankle impairment
* Botulinum toxin injections in PF within the last 4 months before study inclusion
* Medical contraindication for maximal effort
* Neurodegenerative disorders
* Cardiovascular disorders
* History of epilepsy.

Where this trial is running

Créteil

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HemiparesisPoststroke/CVARehabilitationSkeletal muscleEccentric strengthening
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.