Comparing early surgery to 3 days of non-surgical management for acute small bowel obstruction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter randomized controlled trial evaluates the effectiveness of early surgical intervention versus a standard 72-hour non-surgical management approach for patients with uncomplicated acute small bowel obstruction (aSBO). Patients who meet the inclusion criteria will be randomly assigned to either receive standard care or early surgery based on their radiological score. The study aims to assess outcomes such as recovery of gastrointestinal function, morbidity, and mortality rates, with follow-up consultations at 30 and 90 days post-operation. Data will be collected daily during hospitalization and through telephone follow-ups after 12 months to monitor for any recurrence of aSBO.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Admission for acute intestinal obstruction of the small intestine on adhesion or bridle
* Confirmation of the aSBO by a scanner
* Adult patient
* Beneficiary of a social security scheme
* Having signed an informed consent

Exclusion Criteria:

* Indication for urgent surgery (small intestine ischemia, intestinal pain, defence, hemodynamic shock, etc.)
* Pregnancy or breastfeeding
* Poor understanding of the French language
* Person deprived of liberty by judicial or administrative decision
* Person undergoing psychiatric treatment under duress
* Person subject to a legal protection measure
* Person unable to express consent

Where it's running

• University Hospital of Angers
  Angers, France Recruiting
• University Hospital of Tours
  Chambray-lès-Tours, France Recruiting
• University Hospital of Grenoble-Alpes
  Grenoble, France Recruiting
• Hospital of Vendée
  La Roche-sur-Yon, France Recruiting
• University Hospital of Amiens
  Amiens, France Not yet recruiting
• University Hospital of Brest
  Brest, France Not yet recruiting

Study contacts

• Study coordinator: Paul Le Naoures, Dr
• Email: Paul.LeNaoures@chu-angers.fr
• Phone: (0)2 41 35 49 16

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Procalcitonin-guided care for adhesion-related small bowel obstruction

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• Dexamethasone plus supportive care versus supportive care for adhesive small bowel obstruction.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.