Comparing Dual-Energy CT and MRI for Neck Infections
Dual-Energy Computed Tomography (DECT) in Acute Neck Infections: Comparison With Magnetic Resonance Imaging (MRI) (ANI-DECT)
This study is testing whether a new type of CT scan can diagnose neck infections as well as or better than MRI in people who might have these infections.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Turku University Hospital Government |
| Locations | 1 site (Turku) |
| Trial ID | NCT05303922 on ClinicalTrials.gov |
What this trial studies
This prospective study aims to compare the effectiveness of dual-energy computed tomography (DECT) and magnetic resonance imaging (MRI) in diagnosing acute neck infections. Fifty patients suspected of having a neck infection will undergo both imaging modalities, which will be evaluated for their ability to depict edema, inflammation, and abscess characteristics. The hypothesis is that DECT will perform comparably to MRI and better than traditional single-energy CT. This research seeks to provide valuable insights into DECT's diagnostic capabilities in emergency settings.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are suspected of having an acute neck infection.
Not a fit: Patients with severe kidney dysfunction, a history of serious reactions to contrast agents, or incompatible metallic objects in their body may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic accuracy and faster imaging for patients with acute neck infections.
How similar studies have performed: Previous studies have indicated that MRI is superior to traditional CT for neck infections, but the effectiveness of DECT in this context is still being evaluated.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Suspicion of acute neck infection as deemed by the referring physician Exclusion Criteria: * History of a serious adverse reaction to intravenous iodine- or gadolinium-based contrast agent * Severe kidney dysfunction (eGFR \< 30 mL/min/1.73m2) * Foreign metallic objects incompatible with MRI in the body * Inability to give informed consent, as deemed by study physician * Inability to follow study instructions
Where this trial is running
Turku
- Turku University Hospital — Turku, Finland (Recruiting)
Study contacts
- Principal investigator: Jussi Hirvonen, MD, PhD — Turku University Hospital
- Study coordinator: Jussi Hirvonen, MD, PhD
- Email: jussi.hirvonen@tyks.fi
- Phone: +35823130000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.