Comparing different surgical approaches for early-stage lung cancer treatment
Anatomical Segmentectomies for Early Stage Lung Cancer. A Multicenter Analysis of RATS, VATS and Open Approach
This study looks at different types of surgery for early-stage lung cancer to see which method works best for patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 472 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Scientific Institute San Raffaele Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 4 sites (Rozzano, Milan and 3 other locations) |
| Trial ID | NCT06737107 on ClinicalTrials.gov |
What this trial studies
This observational study analyzes the outcomes of robotic segmentectomies performed at four major medical centers, comparing them to video-assisted thoracoscopic surgery (VATS) and open surgical approaches. It aims to assess perioperative complications, surgery duration, lymph node dissection rates, and overall and disease-free survival across these techniques. The study includes patients diagnosed with non-small cell lung cancer (NSCLC) who underwent segmentectomies between January 2010 and December 2023. By evaluating these different surgical methods, the study seeks to provide insights into the most effective approaches for treating early-stage lung cancer.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old who have been diagnosed with non-small cell lung cancer and have undergone segmentectomy.
Not a fit: Patients under 18 years old or those diagnosed with conditions other than non-small cell lung cancer may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and recovery for patients with early-stage lung cancer.
How similar studies have performed: Previous studies have shown promising results with robotic techniques in thoracic surgery, indicating potential for success in this comparative analysis.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pre or post-operative diagnosis of NSCLC surgically treated with pulmonary segmentectomy from 1st January 2010 to the 31st to December 2023. * Age \> then 18 years at the moment of surgery Exclusion Criteria: * Age \< then 18 years at the moment of surgery * diagnosis other than NSCLC
Where this trial is running
Rozzano, Milan and 3 other locations
- Istituto Clinico Humanitas — Rozzano, Milan, Italy (Recruiting)
- Scientific Institute Ospedale San Raffaele — Milan, Italy (Recruiting)
- Istituto Europeo di Oncologia — Milan, Italy (Recruiting)
- Policlinico Universitario Agostino Gemelli — Rome, Italy (Recruiting)
Study contacts
- Study coordinator: Pierluigi Novellis, Medical Doctor
- Email: novellis.pierluigi@hsr.it
- Phone: 0226437202
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.