Comparing different rTMS methods for chronic neuropathic pain relief

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the analgesic effectiveness of three different modes of repetitive Transcranial Magnetic Stimulation (rTMS) in patients suffering from chronic neuropathic pain. Participants will be randomly assigned to receive either classical rTMS, deeper rTMS, or a sham treatment after providing informed consent. They will record their pain intensity daily for one week before treatment and continue to do so during the seven weeks of neurostimulation sessions, followed by a two-week follow-up period. The study will assess the effectiveness of these interventions in managing refractory neuropathic pain.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient's written consent
* Affiliated with social security system
* Male or female, suffering for more than a year from unilateral refractory neuropathic pain: hemi-body, upper limb, lower limb and facial chronic pain.
* Patient whose analgesic treatment, is stable for at least 1 month.
* Patient not responding to conventional treatments
* Prescreening EVN \>3

Exclusion Criteria:

* History of drug addiction, epilepsy, cranial trauma
* History of psychiatric disorder
* Patients previously treated with rTMS
* Patient with intracranial ferromagnetic material or implanted stimulator
* New treatment for less than one month
* Pregnant or Breastfeeding woman
* Patient who does not understand the study protocol
* Persons who are protected under the act.

Where it's running

• Centre de la douleur, CHU Grenoble Alpes
  Grenoble, Isère, France Recruiting

Study contacts

• Principal investigator: Hasan HODAJ, MD — Chuga
• Study coordinator: Hasan HODAJ, MD
• Email: HHodaj@chu-grenoble.fr
• Phone: 04-76-76-52-13

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Using psilocybin to help manage chronic neuropathic pain

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.