Comparing different online weight loss programs for obesity
Adapting Episodic Future Thinking for Behavioral Weight Loss: Comparing Strategies and Characterizing Treatment Response
NA · The Miriam Hospital · NCT05799846
This study is testing which of three online weight loss programs works best for adults with obesity over a year.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 360 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | The Miriam Hospital (other) |
| Locations | 1 site (Providence, Rhode Island) |
| Trial ID | NCT05799846 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of three distinct Internet-delivered behavioral weight loss interventions—Standard Behavioral, PREVENT, and PROMOTE—in adults with obesity. Participants will be randomized to one of the interventions for 12 months, during which they will learn specific cognitive strategies tailored to their assigned program. The study will assess weight change, adherence to weight-related behaviors, and individual characteristics that may predict success, while also monitoring for any potential adverse outcomes. The goal is to determine which program yields the best results and understand the mechanisms behind each approach.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 70 with a BMI between 25 and 45 kg/m2 who have regular Internet access.
Not a fit: Patients currently enrolled in a weight loss program or those with certain medical or psychiatric conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide effective online weight loss strategies tailored to individual needs, improving outcomes for patients with obesity.
How similar studies have performed: Other studies have shown promise in using behavioral interventions for weight loss, suggesting that this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants will be between the ages of 18 and 70, have a BMI between 25 and 45 kg/m2, and have regular (i.e., weekly) access to the Internet, defined as owning a smart phone with Internet capabilities, and/or having a broadband or Wi-Fi connection at home or work. Exclusion Criteria: * Exclusionary criteria include: 1) current enrollment in a weight loss program, 2) currently taking weight loss medications, 3) history of bariatric surgery or planned bariatric surgery in the next 18 months, 4) individuals who are pregnant, nursing, or have plans to become pregnant within the next 18 months, 5) individuals planning to relocate outside the area in the next 18 months, 6) any medical condition for which weight loss would be contraindicated, 7) neurological or psychiatric conditions including but not limited to schizophrenia and bipolar disorder, 8) inability to attend assessments at the Weight Control and Diabetes Research Center in Providence, RI. Individuals with mobility issues, dizziness, or history of heart disease, diabetes, or cancer will be required to provide physician consent prior to enrolling.
Where this trial is running
Providence, Rhode Island
- Weight Control & Diabetes Research Center — Providence, Rhode Island, United States (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Obesity