Comparing different methods of pain management during bariatric surgery
Official title: Comparison of the Efficacy of Celiac Plexus Blockade, Erector Spinae Compartment Blockade (ESP), and Intravenous Lidocaine Infusion Under Opioid-free Anesthesia in Patients Undergoing Bariatric Surgery
Run by Jagiellonian University · NCT06793527 · Data updated 2026-11-12
This study is testing three different ways to manage pain during weight loss surgery to see which one works best while reducing the need for opioids.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Jagiellonian University Academic / other |
| Locations | 1 site (Krakow, Lesser Poland Voivodeship) |
| Status | Recruiting |
| Started | February 6, 2025 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | April 4, 2025 |
| Trial ID | NCT06793527 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years undergoing laparoscopic bariatric surgery who can provide informed consent.
✕Probably not a fit
Patients with a history of drug addiction, chronic pain requiring analgesics, or certain medical conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of three different pain management techniques during laparoscopic bariatric surgery: erector spinae plane (ESP) block, celiac plexus block, and intravenous lidocaine infusion. Patients will be randomly assigned to one of the three groups, with pain intensity assessed at various intervals post-surgery. The goal is to determine which method provides the best analgesia while minimizing opioid use and its associated side effects. All patients will receive a standardized opioid-free anesthesia protocol during the procedure.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies that reduce reliance on opioids in bariatric surgery.
How similar studies have gone: While there is ongoing interest in non-opioid analgesic techniques, this specific comparison of ESP and celiac plexus blocks in bariatric surgery is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients over 18 years who underwent laparoscopic bariatric surgery * Must be able to sign agreement for study Exclusion Criteria: * Patients with a history of allergic reactions to drugs * Patients with a history of drug addiction * Patients with chronic pain who require analgesics * History of hospitalization for psychiatric disorders * Preoperative pulse oximetry (SpO2) \< 95 % * bradycardia (HR\<50bpm) * hypotension * atrioventricular block * intraventricular or sinus block * Blood clotting disorders * Pregnant/lactating women * Cognitive impairment * Unable to read consent
Where it's running
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Department of Intensive Interdisciplinary Care, Collegium Medicum, Jagiellonian University
Krakow, Lesser Poland Voivodeship, Poland Recruiting
Study contacts
- Principal investigator: Tomasz Skladzien, MD PhD — Jagiellonian University
- Study coordinator: Tomasz Skladzien, MD PhD
- Email: tomasz.skladzien@uj.edu.pl
- Phone: 124001800
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.