Comparing different methods of pain management during bariatric surgery
Comparison of the Efficacy of Celiac Plexus Blockade, Erector Spinae Compartment Blockade (ESP), and Intravenous Lidocaine Infusion Under Opioid-free Anesthesia in Patients Undergoing Bariatric Surgery
This study is testing three different ways to manage pain during weight loss surgery to see which one works best while reducing the need for opioids.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Jagiellonian University Academic / other |
| Locations | 1 site (Krakow, Lesser Poland Voivodeship) |
| Trial ID | NCT06793527 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of three different pain management techniques during laparoscopic bariatric surgery: erector spinae plane (ESP) block, celiac plexus block, and intravenous lidocaine infusion. Patients will be randomly assigned to one of the three groups, with pain intensity assessed at various intervals post-surgery. The goal is to determine which method provides the best analgesia while minimizing opioid use and its associated side effects. All patients will receive a standardized opioid-free anesthesia protocol during the procedure.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years undergoing laparoscopic bariatric surgery who can provide informed consent.
Not a fit: Patients with a history of drug addiction, chronic pain requiring analgesics, or certain medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies that reduce reliance on opioids in bariatric surgery.
How similar studies have performed: While there is ongoing interest in non-opioid analgesic techniques, this specific comparison of ESP and celiac plexus blocks in bariatric surgery is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients over 18 years who underwent laparoscopic bariatric surgery * Must be able to sign agreement for study Exclusion Criteria: * Patients with a history of allergic reactions to drugs * Patients with a history of drug addiction * Patients with chronic pain who require analgesics * History of hospitalization for psychiatric disorders * Preoperative pulse oximetry (SpO2) \< 95 % * bradycardia (HR\<50bpm) * hypotension * atrioventricular block * intraventricular or sinus block * Blood clotting disorders * Pregnant/lactating women * Cognitive impairment * Unable to read consent
Where this trial is running
Krakow, Lesser Poland Voivodeship
- Department of Intensive Interdisciplinary Care, Collegium Medicum, Jagiellonian University — Krakow, Lesser Poland Voivodeship, Poland (Recruiting)
Study contacts
- Principal investigator: Tomasz Skladzien, MD PhD — Jagiellonian University
- Study coordinator: Tomasz Skladzien, MD PhD
- Email: tomasz.skladzien@uj.edu.pl
- Phone: 124001800
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.